4-Hydroxy-1-methyl-N-(3-(trifluoromethyl)phenyl)-1H-thieno[3,2-c][1,2]thiazine-3-carboxamide 2,2-dioxide CAS 303987-73-7
| CAS No. | 303987-73-7 |
| Molecular Formula | C15H11F3N2O4S2 |
| Molecular Weight | 404.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Hydroxy-1-methyl-N-(3-(trifluoromethyl)phenyl)-1H-thieno[3,2-c][1,2]thiazine-3-carboxamide 2,2-dioxide is closely related to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-Hydroxy-1-methyl-N-(3-(trifluoromethyl)phenyl)-1H-thieno[3,2-c][1,2]thiazine-3-carboxamide 2,2-dioxide (CAS 303987-73-7), molecular formula C15H11F3N2O4S2 and molecular weight 404.38 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Hydroxy-1-methyl-N-(3-(trifluoromethyl)phenyl)-1H-thieno[3,2-c][1,2]thiazine-3-carboxamide 2,2-dioxide (C15H11F3N2O4S2) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Hydroxy-1-methyl-N-(3-(trifluoromethyl)phenyl)-1H-thieno[3,2-c][1,2]thiazine-3-carboxamide 2,2-dioxide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H11F3N2O4S2 |
| Molecular Weight | 404.38 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
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Recommended Standards
- [(3Z)-2-Oxo-1-{[3-(trifluoromethyl)phenyl]methyl}-2,3-dihydro-1H-indol-3-ylidene]amino 3-methylbutanoate (CAS 321429-89-4)
- Ethyl 2-methyl-5-oxo-1-phenyl-4-((3-(trifluoromethyl)phenyl)amino)-2,5-dihydro-1H-pyrrole-2-carboxylate (CAS 6181-78-8)
- (3AR)-5-(2-hydroxyphenyl)-3a-methyl-6-[3-(trifluoromethyl)benzoyl]-octahydropyrrolo[2,3-b]pyrrol-2-one (CAS 956964-50-4)
- Regadenoson Impurity 20 (CAS 313348-33-3)
- Methyl 2-bromo-4-cyano-3-(trifluoromethyl)benzoate (CAS 1805594-94-8)
- 2-Methyl-4-(oxetan-3-yloxy)benzonitrile (CAS 1599807-43-8)
- n-[4-(chloromethyl)-1,3-thiazol-2-yl]-n-(2,3-dimethylphenyl)acetamide (CAS 857041-74-8)
- 4-Aminoisophthalonitrile (CAS 19619-22-8)
- Bendamustine Impurity 39 (CAS CATO-C4X-127139)
- N-(3-Bromo-4-methylphenyl)-1,3-propanesultam (CAS 1226343-78-7)
- Ethyl 4-fluorobicyclo[2.2.2]Octane-1-carboxylate (CAS 20277-39-8)
- Ethyl 4-((3-(4-methylpiperidin-1-yl)propyl)amino)piperidine-1-carboxylate (CAS 1119451-19-2)
- 3-Bromo-4-hydrazinyl-5-(piperidin-1-ylsulfonyl)pyridine (CAS 1352486-67-9)
- Fragment-[9-31]-Semaglutide (CAS CATO-C4X-2226181)
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