1-[(2,6-Dichlorophenyl)methyl]-2,3,4,5-tetrahydro-1H-1-benzazepin-2-one CAS 303988-08-1
| CAS No. | 303988-08-1 |
| Molecular Formula | C17H15Cl2NO |
| Molecular Weight | 320.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-[(2,6-Dichlorophenyl)methyl]-2,3,4,5-tetrahydro-1H-1-benzazepin-2-one is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-[(2,6-Dichlorophenyl)methyl]-2,3,4,5-tetrahydro-1H-1-benzazepin-2-one (CAS 303988-08-1), molecular formula C17H15Cl2NO and molecular weight 320.21 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 1-[(2,6-Dichlorophenyl)methyl]-2,3,4,5-tetrahydro-1H-1-benzazepin-2-one (C17H15Cl2NO) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 320.21 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H15Cl2NO |
| Molecular Weight | 320.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Dichlorophenyl Standards
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- 1-[(2,4-Dichlorophenyl)methyl]-N-ethyl-1H-1,3-benzodiazol-2-amine (CAS 692733-04-3)
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Recommended Standards
- 1-(5-Bromopyridin-2-yl)-4-(methylsulfonyl)piperazine (CAS 260441-55-2)
- 2-(3,5-Dicarboxyphenyl)-1H-imidazole-4,5-dicarboxylic acid (CAS 2181837-52-3)
- 1-(3,4-Dichlorobenzyl)-1,3,4,5-tetrahydro-2H-benzo[b]azepin-2-one (CAS 303988-02-5)
- 2-Azetidinomethyl-2,3-dichlorobenzophenone (CAS 898755-21-0)
- 2-Amino-5-bromo-4-methoxybenzaldehyde (CAS 1036756-11-2)
- EThyl 3-[(4-nitrophenyl)formamido]propanoate (CAS 172899-47-7)
- (R)-2-(((Benzyloxy)carbonyl)amino)-3-(bicyclo[1.1.1]pentan-1-yl)propanoic acid (CAS 2322921-14-0)
- ethyl 3-(chloromethyl)-5-methyl-1,2-oxazole-4-carboxylate (CAS 266341-73-5)
- Ertapenem Impurity 56 (CAS CATO-C4X-163356)
- 1,7-Difluoroheptan-2-One (CAS 333-06-2)
- 2-((5-(4-Ethoxyphenyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)-N-(4-methoxybenzyl)acetamide (CAS 720667-83-4)
- 3-((Tert-butoxycarbonyl)amino)-2-(3-chlorobenzyl)propanoic acid (CAS 886364-85-8)
- 5-Chloro-2-(phenyldiazenyl)pyridine (CAS 20815-69-4)
- Semaglutide impurity 256 (CAS CATO-C4X-2226256)
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