4-[(4-Chlorophenyl)sulfanyl]-N-(4-methoxyphenyl)-3-nitrobenzamide CAS 303988-23-0

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-[(4-Chlorophenyl)sulfanyl]-N-(4-methoxyphenyl)-3-nitrobenzamide.

4-[(4-Chlorophenyl)sulfanyl]-N-(4-methoxyphenyl)-3-nitrobenzamide (CAS 303988-23-0), molecular formula C20H15ClN2O4S and molecular weight 414.86 g/mol, is a CATO reference standard with documented purity and traceability.

4-[(4-Chlorophenyl)sulfanyl]-N-(4-methoxyphenyl)-3-nitrobenzamide (C20H15ClN2O4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-[(4-Chlorophenyl)sulfanyl]-N-(4-methoxyphenyl)-3-nitrobenzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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