Dimethyl 2,2'-((2-(2-chloro-6-fluorobenzyl)-4-formyl-1,3-phenylene)bis(oxy))diacetate CAS 303994-40-3
| CAS No. | 303994-40-3 |
| Molecular Formula | C20H18ClFO7 |
| Molecular Weight | 424.80 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Dimethyl 2,2'-((2-(2-chloro-6-fluorobenzyl)-4-formyl-1,3-phenylene)bis(oxy))diacetate.
CATO supplies Dimethyl 2,2'-((2-(2-chloro-6-fluorobenzyl)-4-formyl-1,3-phenylene)bis(oxy))diacetate (CAS 303994-40-3), a certified reference material (molecular formula C20H18ClFO7, MW 424.80 g/mol) for analytical method development and quality control.
Owing to a flavonoid core, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, Dimethyl 2,2'-((2-(2-chloro-6-fluorobenzyl)-4-formyl-1,3-phenylene)bis(oxy))diacetate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 424.80 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H18ClFO7 |
| Molecular Weight | 424.80 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
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Recommended Standards
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- Methyl 3-(2-chloro-6-fluorophenyl)-5-[(1Z)-1-(dimethylamino)-4-ethoxy-3,4-dioxobut-1-en-2-yl]-1,2-oxazole-4-carboxylate (CAS 1164473-36-2)
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- 2-[(4-Fluorophenyl)sulfanyl]-3-[3-(trifluoromethyl)phenyl]quinoline (CAS 339103-51-4)
- 2-(4-(4-Methoxyphenyl)-2-methyl-6-oxopyrimidin-1(6H)-yl)acetic acid (CAS 1710833-99-0)
- 7-Chloro-6-iodo-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 1021913-07-4)
- 4-(2-(Pyridin-3-yl)acetamido)benzoic acid (CAS 1480111-47-4)
- D-Tyr10-Tirzepatide (CAS CATO-CPTD788922)
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