(2E)-3-[(4-Methylphenyl)amino]-2-(thiophen-2-yl)prop-2-enenitrile CAS 303995-13-3

Purity 97%+In StockPharmaceutical Standards
CAS No.303995-13-3
Molecular FormulaC14H12N2S
Molecular Weight240.32 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(2E)-3-[(4-Methylphenyl)amino]-2-(thiophen-2-yl)prop-2-enenitrile CAS 303995-13-3 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (2E)-3-[(4-Methylphenyl)amino]-2-(thiophen-2-yl)prop-2-enenitrile.

CATO supplies (2E)-3-[(4-Methylphenyl)amino]-2-(thiophen-2-yl)prop-2-enenitrile (CAS 303995-13-3), a certified reference material (molecular formula C14H12N2S, MW 240.32 g/mol) for analytical method development and quality control.

Structurally, (2E)-3-[(4-Methylphenyl)amino]-2-(thiophen-2-yl)prop-2-enenitrile (C14H12N2S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 240.32 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (2E)-3-[(4-Methylphenyl)amino]-2-(thiophen-2-yl)prop-2-enenitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC14H12N2S
Molecular Weight240.32 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Nitrogen Atoms2
Sulfur Atoms1

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