N-(4-chlorophenyl)-1-oxo-2-(pyridin-3-ylmethyl)-1,2-dihydroisoquinoline-4-carboxamide CAS 303995-22-4
| CAS No. | 303995-22-4 |
| Molecular Formula | C22H16ClN3O2 |
| Molecular Weight | 389.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-(4-chlorophenyl)-1-oxo-2-(pyridin-3-ylmethyl)-1,2-dihydroisoquinoline-4-carboxamide (CAS 303995-22-4), molecular formula C22H16ClN3O2 and molecular weight 389.83 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, N-(4-chlorophenyl)-1-oxo-2-(pyridin-3-ylmethyl)-1,2-dihydroisoquinoline-4-carboxamide (C22H16ClN3O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 16.0, corresponding to approximately 16 ring(s) or double-bond equivalent(s). With a molecular weight of 389.83 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H16ClN3O2 |
| Molecular Weight | 389.83 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
- Indibulin (CAS 204205-90-3)
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- Amlodipine Impurity 77 (CAS 2802443-91-8)
- 1-Isopropyl-1H-imidazole-4-carbonitrile (CAS 1159733-95-5)
- 4-{[(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)methyl]amino}benzamide (CAS 909344-67-8)
- 1-Methyl-4-(pyrrolidin-3-yloxy)-1H-indole (CAS 786607-54-3)
- N-(3-formyl-4-methylpyridin-2-yl)-2,2-dimethylpropanamide (CAS 216678-81-8)
- Copper, (L-aspartato)- (CAS 30272-90-3)
- (1-(Thieno[3,2-d]pyrimidin-4-yl)piperidin-4-yl)methanol (CAS 910037-26-2)
- N'-Benzylidene-2-((5-((4-chlorobenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)acetohydrazide (CAS 406202-01-5)
- 4-(Cyclopropyl(imino)methyl)-3-methylthiomorpholine 1,1-dioxide (CAS 1594679-01-2)
- 675148-48-8 4-Chloromethyl-5-methyl-2-(pyridin-3-yl)oxazole MFCD08056336 (CAS 675148-48-8)
- Immunstimulating Peptide, human (CAS 94773-24-7)
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