N-Methoxy-N-methyl-N-[5-oxo-2-(trifluoromethyl)-5H-chromeno[2,3-b]pyridin-3-yl]urea CAS 303995-28-0
| CAS No. | 303995-28-0 |
| Molecular Formula | C16H12F3N3O4 |
| Molecular Weight | 367.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 367.28 g/mol gives N-Methoxy-N-methyl-N-[5-oxo-2-(trifluoromethyl)-5H-chromeno[2,3-b]pyridin-3-yl]urea distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
N-Methoxy-N-methyl-N-[5-oxo-2-(trifluoromethyl)-5H-chromeno[2,3-b]pyridin-3-yl]urea (CAS 303995-28-0) is a high-purity analytical reference standard with the molecular formula C16H12F3N3O4 and a molecular weight of 367.28 g/mol.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, N-Methoxy-N-methyl-N-[5-oxo-2-(trifluoromethyl)-5H-chromeno[2,3-b]pyridin-3-yl]urea is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 367.28 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H12F3N3O4 |
| Molecular Weight | 367.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related N Standards
- N-(2-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-2-phenylacetamide (CAS 2045409-68-3)
- PHenyl-7-methoxy-2',5'-dioxospiro[2,3-dihydroquinoline-4,4'-imidazolidine]-1-carboxylate (CAS 1258652-79-7)
- 6-Methoxy-1H-indol-5-ol (CAS 2380-83-8)
- Methyl 4-(5-(2-methoxy-2-oxoethyl)-4-phenylthiazol-2-yl)benzoate (CAS 861209-65-6)
- 4-Methoxy-1-methyl-1H-pyrazolo[3,4-d]pyrimidine (CAS 5334-53-2)
- 4-Methoxy-N-(2-(2-(1-methylpiperidin-2-yl)propyl)phenyl)benzamide (CAS 58754-01-1)
- Ethyl 2-({5-methoxy-4-[(4-methoxyphenyl)sulfanyl]pyrimidin-2-yl}sulfanyl)acetate (CAS 338423-26-0)
- (E)-4-Methoxy-N-(2-(2-(pyridin-4-yl)vinyl)phenyl)benzenesulfonamide (CAS 173528-92-2)
Recommended Standards
- N,N-Dibenzyl-5-bromo-3-methylpyridin-2-amine (CAS 664988-32-3)
- Pyrimido[5,4-d]Pyrimidine Impurity 7 (CAS 36926-31-5)
- 5-Bromo-N-(4,7-dimethylbenzo[d]thiazol-2-yl)thiophene-2-carboxamide (CAS 905692-99-1)
- tert-Butyl 5-(4-bromophenyl)-2,5-diazabicyclo[2.2.2]octane-2-carboxylate (CAS 2097819-97-9)
- N-(2-(3-bromobenzoyl)-4,5-dimethoxyphenyl)-4-methylbenzenesulfonamide (CAS 373370-93-5)
- 4-Bromo-3-methoxy-N,N-dipropylbenzenesulfonamide (CAS 898645-36-8)
- (9H-fluoren-9-yl)methyl 3-bromo-4-oxopiperidine-1-carboxylate (CAS 562827-16-1)
- Loxoprofen Impurity 69 (CAS CATO-C4X-148869)
- N6-Benzoyl-7’-OH-morpholino adenine (CAS 139290-78-1)
- 2-tert-Butylpyrimidine-4-carboxylic acid (CAS 847955-90-2)
- tert-Butyl 1,1-dimethyl-4-oxo-1,2-dihydrobenzo[d][1,3]azasiline-3(4H)-carboxylate (CAS 2222440-59-5)
- 3-(1h-Benzo[d]imidazol-2-yl)-1-(4-fluorophenyl)-2,5-dihydro-1h-pyrrol-2-amine (CAS 459137-97-4)
- (R)-6-Bromo-N-(1-(4-fluorophenyl)ethyl)-3-nitroquinolin-4-amine (CAS 2123481-32-1)
- Fragment-[9-31]-Semaglutide (CAS CATO-C4X-2226181)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com