3-Chloro-N-[(E)-2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethenyl]aniline CAS 303997-77-5
| CAS No. | 303997-77-5 |
| Molecular Formula | C14H9Cl2F3N2 |
| Molecular Weight | 333.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Chloro-N-[(E)-2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethenyl]aniline (CAS 303997-77-5), molecular formula C14H9Cl2F3N2 and molecular weight 333.14 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution, 3-Chloro-N-[(E)-2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethenyl]aniline is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 333.14 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-Chloro-N-[(E)-2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethenyl]aniline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H9Cl2F3N2 |
| Molecular Weight | 333.14 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 2-Chloro-N-[(E)-2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethenyl]aniline (CAS 1164523-95-8)
- 4-Chloro-N-[(E)-2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethenyl]aniline (CAS 338978-19-1)
- 3-Chloro-5-(4-chlorophenyl)-4-(4-fluorophenyl)-6-methylpyridazine (CAS 2034157-25-8)
- (5-Chloro-1-methyl-3-phenyl-1H-pyrazol-4-yl)(4-chlorophenyl)methanol (CAS 956507-62-3)
- 2-Chloro-1-(8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl)-2,2-difluoroethan-1-one (CAS 1823183-01-2)
- 4-Chloro-6-[(4-chlorophenyl)sulfanyl]-3-phenylpyridazine (CAS 477872-26-7)
- 1-Chloro-4-{[(4-chlorophenyl)sulfanyl]methanesulfonyl}benzene (CAS 59662-66-7)
- 3-Chloro-5-((((3-chloro-1,2,4-thiadiazol-5-yl)sulfinyl)methyl)thio)-1,2,4-thiadiazole (CAS 135379-15-6)
Recommended Standards
- 1,5-Diamino-2-bromo-8-hydroxyanthracene-9,10-dione (CAS 242134-36-7)
- 4-Bromo-10-methyl-2-nitroacridin-9(10H)-one (CAS 90019-40-2)
- Methyl 2-(5-bromopyridin-3-yl)benzo[d]oxazole-5-carboxylate (CAS 1706459-12-2)
- 2-(5-Bromopyridin-3-yl)benzo[d]oxazole-5-carbohydrazide (CAS 1706434-37-8)
- 5-Nitroisothiazole-3-carboxylic acid, 97% (CAS 36778-15-1)
- (4-Ethoxyphenyl)(phenyl)methanamine hydrochloride (CAS 879663-16-8)
- Gilvocarcin M (CAS 77879-89-1)
- Methyl 6-(1-ethyl-1H-pyrazol-3-yl)-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1172751-82-4)
- tert-butyl 3-mercaptopyrrolidine-1-carboxylate (CAS 371240-66-3)
- Mephosfolan (CAS 950-10-7)
- (S)-N-(4-(2-Chloro-1-hydroxyethyl)phenethyl)methanesulfonamide (CAS 1176485-19-0)
- 3,5-Dimethyl-1-phenyl-1H-pyrazole-4-carbonitrile (CAS 23198-55-2)
- Trandolapril-D5 (CAS 1356847-98-7)
- [Plus-β-Ala28]-Semaglutide (CAS CATO-C4X-2226221)
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