5-[(3,4-Dichlorophenyl)sulfanyl]-N-(2,4-difluorophenyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide CAS 303998-52-9
| CAS No. | 303998-52-9 |
| Molecular Formula | C18H10Cl2F5N3OS |
| Molecular Weight | 482.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
5-[(3,4-Dichlorophenyl)sulfanyl]-N-(2,4-difluorophenyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide (CAS 303998-52-9), molecular formula C18H10Cl2F5N3OS and molecular weight 482.25 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 5-[(3,4-Dichlorophenyl)sulfanyl]-N-(2,4-difluorophenyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 482.25 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H10Cl2F5N3OS |
| Molecular Weight | 482.25 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Dichlorophenyl Standards
- 5-((2,4-Dichlorophenyl)thio)-N-(2,4-difluorophenyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide (CAS 303998-54-1)
- (2E)-1-{3-[(2,4-dichlorophenyl)methoxy]phenyl}-3-{[4-(trifluoromethoxy)phenyl]amino}prop-2-en-1-one (CAS 478040-02-7)
- (2E)-1-{4-[(2,4-dichlorophenyl)methoxy]phenyl}-3-{[4-(trifluoromethoxy)phenyl]amino}prop-2-en-1-one (CAS 478033-88-4)
- 2-(2,4-Dichlorophenyl)-3',5-dimethyl-1'-(4-phenylthiazol-2-yl)-1'H,2H-[3,4'-bipyrazol]-5'-ol (CAS 246021-97-6)
- 2'-(4-(2,4-Dichlorophenyl)thiazol-2-yl)-5,5'-dimethyl-2-phenyl-1',2'-dihydro-2H,3'H-[3,4'-bipyrazol]-3'-one (CAS 245039-21-8)
- (5-(3,4-Dichlorophenyl)-2,3-dihydro-1H-pyrrolizine-6,7-diyl)bis(methylene) bis(isopropylcarbamate) (CAS 74296-42-7)
- N-(2,4-dichlorophenyl)-2-((2-((4-methylphenyl)sulfonamido)phenyl)thio)acetamide (CAS 477869-04-8)
- 4-[5-(2,4-Dichlorophenyl)-1H-pyrazol-3-yl]-1-(2-nitrobenzenesulfonyl)piperidine (CAS 1031236-58-4)
Recommended Standards
- 3-Chloro-2-(3-{4-[(2-chloro-6-fluorophenyl)methoxy]phenyl}-1H-pyrazol-1-yl)-5-(trifluoromethyl)pyridine (CAS 477711-65-2)
- (2-(Bis(perfluorophenyl)boryl)cyclopenta-1,4-dien-1-yl)trimethylsilane (CAS 462109-75-7)
- 6-((3-(4-Bromophenyl)-1,2,4-oxadiazol-5-yl)methyl)-3-(3-fluorobenzyl)-3,6-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one (CAS 1223903-71-6)
- Sulfo-SIAB (CAS 106145-13-5)
- 1-((6-Chloroimidazo[1,2-a]pyridin-2-yl)methyl)-1H-pyrazole-3-carboxylic acid (CAS 1707375-79-8)
- 10,15-Dihydro-5,5,10,10,15,15-hexamethyl-5H-tribenzo[a,f,k]trindene (CAS 597554-76-2)
- 1-(2-Bromopropyl)-3-chlorobenzene (CAS 216581-36-1)
- 6-Bromo-4,4-dimethyl-1,2,3,4-tetrahydroquinoline (CAS 135631-91-3)
- 4-Ethynylfuran-2-carbaldehyde (CAS 1344700-96-4)
- 2-((5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)oxy)ethan-1-ol (CAS 1339926-59-8)
- 3-(Benzylthio)-1-(o-tolyl)-6,7-dihydro-5H-cyclopenta[c]pyridine-4-carbonitrile (CAS 439096-81-8)
- Methyl 1-(4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl)-1H-pyrazole-3-carboxylate (CAS 1707562-48-8)
- Naproxen Impurity 49 (CAS CATO-C4X-170849)
- Semaglutide impurity 31 (CAS CATO-C4X-222631)
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