3-(2-Chloro-6-fluorophenyl)-N-(((4-chlorophenyl)carbamoyl)carbamothioyl)-5-methylisoxazole-4-carboxamide CAS 303998-81-4
| CAS No. | 303998-81-4 |
| Molecular Formula | C19H13Cl2FN4O3S |
| Molecular Weight | 467.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 467.30 g/mol gives 3-(2-Chloro-6-fluorophenyl)-N-(((4-chlorophenyl)carbamoyl)carbamothioyl)-5-methylisoxazole-4-carboxamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-(2-Chloro-6-fluorophenyl)-N-(((4-chlorophenyl)carbamoyl)carbamothioyl)-5-methylisoxazole-4-carboxamide (CAS 303998-81-4) is a high-purity analytical reference standard with the molecular formula C19H13Cl2FN4O3S and a molecular weight of 467.30 g/mol.
The molecular framework of 3-(2-Chloro-6-fluorophenyl)-N-(((4-chlorophenyl)carbamoyl)carbamothioyl)-5-methylisoxazole-4-carboxamide (C19H13Cl2FN4O3S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(2-Chloro-6-fluorophenyl)-N-(((4-chlorophenyl)carbamoyl)carbamothioyl)-5-methylisoxazole-4-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H13Cl2FN4O3S |
| Molecular Weight | 467.30 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 5-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)-N-(4-chlorophenyl)thiophene-2-sulfonamide (CAS 306976-60-3)
- 3-Chloro-2-[(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)methyl]-5-(trifluoromethyl)pyridine (CAS 338410-46-1)
- 5-Chloro-3-(3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl)-1-(2,4-dichlorobenzyl)pyridin-2(1H)-one (CAS 477858-13-2)
- 3-Chloro-5-(5-chlorofuran-2-yl)-2-(3,4-dichlorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine (CAS 691868-56-1)
- 4-Chloro-N-[1-(4-ethyl-5-{[(4-methoxyphenyl)methyl]sulfanyl}-4H-1,2,4-triazol-3-yl)ethyl]benzene-1-sulfonamide (CAS 338954-05-5)
- 2-(4-(5-Chloro-2-methylphenyl)piperazin-1-yl)-7-(4-methoxyphenyl)thieno[3,2-d]pyrimidin-4(1H)-one (CAS 1226430-62-1)
- N'-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-3-(2,6-dichlorophenyl)-N'-methyl-4,5-dihydroisoxazole-5-carbohydrazide (CAS 338774-96-2)
- 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}-5-[(E)-2-[(2,4-dimethylphenyl)amino]ethenyl]-1,2-thiazole-4-carbonitrile (CAS 338413-06-2)
Recommended Standards
- N-(5-cyano-2-((2,6-dichlorophenyl)thio)phenyl)-3-(trifluoromethyl)benzamide (CAS 303147-52-6)
- 1-(2,3-Dibromopropyl)-2,3,5,6-tetrafluoro-4-(trichloromethyl)benzene (CAS 1244856-09-4)
- N-(3,5-dichlorophenyl)-1-((3-(trifluoromethyl)phenyl)sulfonyl)pyrrolidine-2-carboxamide (CAS 317822-01-8)
- (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(5-bromopyridin-2-yl)propanoic acid (CAS 282734-37-6)
- 4'-(Hydroxymethyl)-[1,1'-biphenyl]-2-ol (CAS 1255638-72-2)
- (2S)-2-amino-3-(3-ethylphenyl)propanoic acid (CAS 1269902-53-5)
- 6-(Dimethylamino)-4-methylnicotinic acid (CAS 951260-15-4)
- {4-[(4-chlorophenyl)methoxy]-3-methylphenyl}boronic acid (CAS 475652-18-7)
- (3-amino-1-isopropyl-1H-pyrazol-5-yl)methanol (CAS 1245773-09-4)
- 6-Bromo-2,3-dihydro-1H-indene-1-carboxylic acid (CAS 52651-16-8)
- 2-(1-((3-Amino-4-bromo-1h-pyrazol-1-yl)methyl)cyclopropyl)acetonitrile (CAS 1494097-03-8)
- 2-Amino-6-(tert-butyl)-N-(2-ethoxyphenyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide (CAS 433240-80-3)
- (1S,2S)-4-methoxybenzyl 2-((S)-4-((9H-xanthen-9-yl)methyl)-1-(4-methoxybenzyl)-2,5-dioxoimidazolidin-4-yl)cyclopropanecarboxylate (CAS 201851-13-0)
- Sperm Activating Peptide, Sea Urchin (CAS 140653-27-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com