(E)-4-(2-(3-chlorobenzoyl)hydrazinyl)-4-oxobut-2-enoic acid CAS 304456-83-5
| CAS No. | 304456-83-5 |
| Molecular Formula | C11H9ClN2O4 |
| Molecular Weight | 268.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (E)-4-(2-(3-chlorobenzoyl)hydrazinyl)-4-oxobut-2-enoic acid.
CATO supplies (E)-4-(2-(3-chlorobenzoyl)hydrazinyl)-4-oxobut-2-enoic acid (CAS 304456-83-5), a certified reference material (molecular formula C11H9ClN2O4, MW 268.65 g/mol) for analytical method development and quality control.
The molecular framework of (E)-4-(2-(3-chlorobenzoyl)hydrazinyl)-4-oxobut-2-enoic acid (C11H9ClN2O4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H9ClN2O4 |
| Molecular Weight | 268.65 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related E Standards
- Ethyl 2-(3-chlorobenzoyl)-3-methylbutanoate (CAS 1285476-25-6)
- 1-(4-Chlorobenzoyl)piperidine-2-carboxylic acid (CAS 1103295-13-1)
- 4-(2-Chlorobenzoyl)isoquinoline (CAS 1187169-58-9)
- 4-(2-Chlorobenzoyl)quinoline (CAS 1706436-14-7)
- 1-(2-Chlorobenzoyl)piperidine-3-carboxylic acid (CAS 926220-63-5)
- 1-(2-Chlorobenzoyl)piperidine-4-carboxylic Acid (CAS 352673-16-6)
- 1-(4-Chlorobenzoyl)piperidine-3-carboxylic acid (CAS 436093-15-1)
- 1-(4-Chlorobenzoyl)piperidine-4-carboxylic acid (CAS 379724-54-6)
Recommended Standards
- 5-Chloro-4-(fluorosulfonyl)-2-methoxybenzoic acid (CAS 1955558-41-4)
- 2-(6-Chloro-7-hydroxy-4-methyl-2-oxo-2H-chromen-3-yl)acetic acid (CAS 855287-83-1)
- 5-Chloro-6-methoxy-4-methyl-8-nitroquinolin-2(1H)-one (CAS 189746-23-4)
- 2-[(6-chloro-4-methyl-2-oxo-2h-chromen-7-yl)oxy]acetic acid (CAS 326102-48-1)
- (Ethylthio)aceticacid (CAS 627-04-3)
- 5-METHOXY-N-METHYLNAPHTHALEN-1-AMINE (CAS 61735-50-0)
- 3-(2-((tert-Butyldimethylsilyl)oxy)ethyl)cyclopentanone (CAS 93131-85-2)
- 4-(3-((tert-Butyldimethylsilyl)oxy)propyl)-2-isopropylpyridin-3-amine (CAS 2641027-63-4)
- 2-(2-(Chloromethyl)pyrrolidin-1-yl)acetic acid (CAS 1353947-13-3)
- N-(3-chlorophenyl)-2-((2,3,4,5,6-pentamethylbenzyl)thio)acetamide (CAS 329079-23-4)
- (E)-3-((4-bromophenyl)amino)-1-(2,5-dimethylthiophen-3-yl)prop-2-en-1-one (CAS 860644-76-4)
- (4-Chloropyrimidin-5-yl)methanol (CAS 389799-45-5)
- Ethyl 1-oxo-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-7-carboxylate (CAS 1338563-13-5)
- Endo-Pro36-Tirzepatide (CAS CATO-CPTD788688)
Why CATO?
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