5-Bromo-2-chloro-4-fluoroaniline CAS 305795-89-5
| CAS No. | 305795-89-5 |
| Molecular Formula | C6H4BrClFN |
| Molecular Weight | 224.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Bromo-2-chloro-4-fluoroaniline is closely related to a nitrile group, fluorine/chlorine/bromine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-Bromo-2-chloro-4-fluoroaniline (CAS 305795-89-5), molecular formula C6H4BrClFN and molecular weight 224.46 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Bromo-2-chloro-4-fluoroaniline (C6H4BrClFN) is characterized by a nitrile group, fluorine/chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-Bromo-2-chloro-4-fluoroaniline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H4BrClFN |
| Molecular Weight | 224.46 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 4-Bromo-2-chloro-5-fluoroaniline (CAS 1000572-63-3)
- 5-Bromo-4-chloro-2-fluoroaniline (CAS 111010-07-2)
- (4-BROMO-3-CHLORO-2-FLUOROPHENYL)AMINE 115843-99-7 4-BROMO-3-CHLORO-2-FLUOROANILINE 4-BROMO-3-CHLORO-2-FLUOROBENZENAMINE BC002759 BUTTPARK 89\07-45 (CAS 115843-99-7)
- 4-Bromo-5-chloro-2-fluoroaniline (CAS 116369-24-5)
- 2-Bromo-4-chloro-5-fluoroaniline (CAS 120694-11-3)
- 3-Bromo-6-chloro-5-fluoro-2-methylpyridine (CAS 1211520-20-5)
- 2-Bromo-5-(chloromethyl)-3-fluoropyridine (CAS 1227489-73-7)
- 2-Bromo-4-(chloromethyl)-5-fluoropyridine (CAS 1227493-80-2)
Recommended Standards
- 5-(Bromomethyl)-2-chloro-3-fluoropyridine (CAS 904745-61-5)
- 5-Bromo-3-chloro-2-fluoro-4-methylpyridine (CAS 2682115-69-9)
- 4-Bromo-2-chloro-6-fluoroaniline (CAS 885453-49-6)
- 2,6-Dimethyl-4-hydroxybenzaldehyde (CAS 102783-03-9)
- Ethyl 3-(bromomethyl)-1-benzofuran-2-carboxylate (CAS 29115-34-2)
- Propan-2-yl 2-(methylamino)acetate (CAS 93378-87-1)
- 2-Hydroxy-3'-(pyrrolidin-1-ylsulfonyl)-[1,1'-biphenyl]-4-carboxylic acid (CAS 1262011-26-6)
- 4-Benzhydryl-N-(2-fluorophenyl)piperazine-1-carboxamide (CAS 893340-18-6)
- n-(1-(4-Fluorophenyl)propyl)cyclopropanamine (CAS 926198-25-6)
- Chloromethyltris(trimethylsiloxy)silane (CAS 41919-30-6)
- Pyridine-2,3-diamine dihydrochloride (CAS 71477-20-8)
- 6-Ethyl-1-[(4-methoxyphenyl)methyl]-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1120284-75-4)
- Methyl 2-ethylfuran-3-carboxylate (CAS 141764-83-2)
- Compstatin control peptide (CAS 301544-78-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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