2,4,6-Trimethyl-N-[4-(trifluoromethyl)benzyl]benzenesulfonamide CAS 305849-16-5
| CAS No. | 305849-16-5 |
| Molecular Formula | C17H18F3NO2S |
| Molecular Weight | 357.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 357.39 g/mol gives 2,4,6-Trimethyl-N-[4-(trifluoromethyl)benzyl]benzenesulfonamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2,4,6-Trimethyl-N-[4-(trifluoromethyl)benzyl]benzenesulfonamide (CAS 305849-16-5) is a high-purity analytical reference standard with the molecular formula C17H18F3NO2S and a molecular weight of 357.39 g/mol.
The molecular framework of 2,4,6-Trimethyl-N-[4-(trifluoromethyl)benzyl]benzenesulfonamide (C17H18F3NO2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2,4,6-Trimethyl-N-[4-(trifluoromethyl)benzyl]benzenesulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H18F3NO2S |
| Molecular Weight | 357.39 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Trimethyl Standards
- N-(2,5,6-trimethyl-1-(3-methylbenzyl)-1H-benzo[d]imidazol-4-yl)methanesulfonamide (CAS 866048-86-4)
- 1,7,7-Trimethyl-3-(pyrrolidin-1-ylmethyl)bicyclo[2.2.1]heptan-2-yl 4-aminobenzoate (CAS 17066-42-1)
- 2,4,6-Trimethyl-3-(5-methyl-4-phenylisoxazol-3-yl)benzenesulfonamide (CAS 775344-85-9)
- 6,14,14-Trimethyl-10-[(E)-2-phenylethenyl]-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6-tetraen-12-one (CAS 1025658-27-8)
- 3,3,4-Trimethyl-1-(1-(2-morpholinoethyl)-1H-indol-3-yl)pent-4-en-1-one (CAS 1616469-10-3)
- 2,2,4-Trimethyl-1,3-pentanediol dibenzoate (CAS 68052-23-3)
- 2,4,6-Trimethyl-N-(2-(pyridin-3-yl)pyrimidin-4-yl)benzenesulfonamide (CAS 439108-35-7)
- Trimethyl(2-(triphenylsilyl)ethyl)silane (CAS 102105-77-1)
Recommended Standards
- 2-((3-Cyano-6-cyclopropyl-4-(trifluoromethyl)pyridin-2-yl)thio)-N,N-diethylacetamide (CAS 664999-71-7)
- 2-{phenyl[(1,3-thiazol-2-yl)amino]phosphoroso}-1,3-benzothiazole (CAS 262603-96-3)
- 2-((3-Cyano-4-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[b]pyridin-2-yl)thio)-N,N-diethylacetamide (CAS 626221-50-9)
- 5-(Benzyl(tert-butoxycarbonyl)amino)-4,4-difluoro-2-methylpentanoic acid (CAS 2101206-20-4)
- (S)-2-Amino-N-methyl-N-(4-(methylthio)benzyl)propanamide (CAS 1304396-72-2)
- Methyl 7-fluoro-1-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylate (CAS 1785760-67-9)
- 3-((4-Fluorobenzyl)oxy)-5-nitro-1H-indazole (CAS 1365939-34-9)
- (5-chloro-6-fluoropyridin-3-yl)boronic acid (CAS 1366482-32-7)
- Methyl 2-((6-amino-3,5-dicyano-4-(4-methoxyphenyl)pyridin-2-yl)thio)acetate (CAS 374913-42-5)
- 9H-fluorene-2,7-disulfonyl dichloride (CAS 1835-76-3)
- 5-((4-Acetylphenoxy)methyl)furan-2-carboxylic acid (CAS 832740-35-9)
- 6-Bromo-3-formylchromone 6-Bromo-4-oxo-4H-1-benzopyran-3-carboxaldehyde 6-Bromochromone-3-carboxaldehyde 6-Bromo-4-oxo-4H-chromene-3-carbaldehyde 52817-12-6 (CAS 52817-12-6)
- 1-(3-Chloropropyl)pyrrolidine oxalate(1:x) (CAS 1022112-22-6)
- Semaglutide impound 212 (CAS CATO-C4X-2226212)
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