4-[(2E)-3-(2,4-Dichlorophenyl)prop-2-enoyl]phenyl thiophene-2-carboxylate CAS 306730-08-5
| CAS No. | 306730-08-5 |
| Molecular Formula | C20H12Cl2O3S |
| Molecular Weight | 403.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-[(2E)-3-(2,4-Dichlorophenyl)prop-2-enoyl]phenyl thiophene-2-carboxylate (CAS 306730-08-5), molecular formula C20H12Cl2O3S and molecular weight 403.28 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-[(2E)-3-(2,4-Dichlorophenyl)prop-2-enoyl]phenyl thiophene-2-carboxylate (C20H12Cl2O3S) is characterized by a steroid core, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H12Cl2O3S |
| Molecular Weight | 403.28 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related E Standards
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Recommended Standards
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