3-[(2,4-Dimethoxyphenyl)methyl]-3-(4-iodophenyl)-1-phenylthiourea CAS 306730-63-2
| CAS No. | 306730-63-2 |
| Molecular Formula | C22H21IN2O2S |
| Molecular Weight | 504.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 3-[(2,4-Dimethoxyphenyl)methyl]-3-(4-iodophenyl)-1-phenylthiourea (CAS 306730-63-2), a certified reference material (molecular formula C22H21IN2O2S, MW 504.38 g/mol) for analytical method development and quality control.
Structurally, 3-[(2,4-Dimethoxyphenyl)methyl]-3-(4-iodophenyl)-1-phenylthiourea (C22H21IN2O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, iodine substitution. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 504.38 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H21IN2O2S |
| Molecular Weight | 504.38 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Dimethoxyphenyl Standards
- 1-(1-(2,5-Dimethoxyphenyl)-2-methyl-5-(4-(methylsulfonyl)phenyl)-1H-pyrrol-3-yl)-N-(4-methoxyphenyl)methanimine (CAS 478032-28-9)
- 4-[(2Z)-3-(2,4-Dimethoxyphenyl)prop-2-enoyl]phenyl 4-bromobenzene-1-sulfonate (CAS 331461-46-2)
- Ethyl 7-(3,4-dimethoxyphenyl)-4-(4-(methoxycarbonyl)phenyl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate (CAS 333308-91-1)
- 5-(2,5-Dimethoxyphenyl)-3-hydroxy-4-(4-isopropoxy-2-methylbenzoyl)-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one (CAS 385385-72-8)
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- Ethyl 7-(3,4-dimethoxyphenyl)-2-methyl-4-(4-methyl-3-nitrophenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate (CAS 503591-61-5)
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Recommended Standards
- 6-Iodopravadoline (CAS 164178-33-0)
- 5-(5-Bromo-6-methoxynaphthalen-2-yl)-3-(3,4-dimethoxyphenyl)-6-methylpyrazolo[1,5-a]pyrimidine (CAS 866144-88-9)
- N'-[(1E)-[3-(4-Fluorophenyl)-1H-pyrazol-4-yl]methylidene]-2,5-bis(2,2,2-trifluoroethoxy)benzohydrazide (CAS 477711-42-5)
- Mometasone Impurity 30 (CAS CATO-C4X-170430)
- 2-Bromo-4-chloro-1H-imidazo[4,5-c]pyridine (CAS 1638767-42-6)
- 1-(2-(4-Hydroxynaphthalen-1-yl)benzofuran-3-yl)ethanone (CAS 61639-35-8)
- (4-Amino-3-chlorophenyl)boronic acid (CAS 948593-57-5)
- 3-(5-Methyl-1,2,4-oxadiazol-3-yl)benzoyl chloride (CAS 522646-39-5)
- Yttrium(III) perchlorate, 50% aqueous solution (99.9%-Y) (REO) (CAS 14017-56-2)
- 1,3,6-Trichlorodibenzofuran (CAS 83704-39-6)
- Fmoc-Pro(3R-Me)-OH (CAS 928330-94-3)
- tert-Butyl (5-(2-aminoethyl)pyridin-2-yl)carbamate (CAS 637015-72-6)
- 5-Methoxy-2-methylpyrimidine-4-carboxylic acid (CAS 113949-10-3)
- Semaglutide Impurity 8 (CAS CATO-C4X-22268)
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