5-Chloro-N-(4-sulfamoylphenyl)thiophene-2-carboxamide CAS 306738-77-2

Purity 97%+In StockPharmaceutical Standards
CAS No.306738-77-2
Molecular FormulaC11H9ClN2O3S2
Molecular Weight316.78 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Chloro-N-(4-sulfamoylphenyl)thiophene-2-carboxamide CAS 306738-77-2 chemical structure

Description

5-Chloro-N-(4-sulfamoylphenyl)thiophene-2-carboxamide (CAS 306738-77-2) is a high-purity analytical reference standard with the molecular formula C11H9ClN2O3S2 and a molecular weight of 316.78 g/mol.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, 5-Chloro-N-(4-sulfamoylphenyl)thiophene-2-carboxamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 316.78 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-Chloro-N-(4-sulfamoylphenyl)thiophene-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H9ClN2O3S2
Molecular Weight316.78 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl-containing
Nitrogen Atoms2
Sulfur Atoms2

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