3-Bromo-4-fluoro-1,1'-biphenyl CAS 306935-88-6
| CAS No. | 306935-88-6 |
| Molecular Formula | C12H8BrF |
| Molecular Weight | 251.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Bromo-4-fluoro-1,1'-biphenyl (CAS 306935-88-6), molecular formula C12H8BrF and molecular weight 251.09 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-Bromo-4-fluoro-1,1'-biphenyl (C12H8BrF) is characterized by fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-Bromo-4-fluoro-1,1'-biphenyl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H8BrF |
| Molecular Weight | 251.09 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 1-Bromo-3-(4-fluorophenyl)benzene (CAS 10540-35-9)
- 2-Bromo-2'-fluoro-biphenyl (CAS 1554-05-8)
- 5-Bromo-2-fluorobiphenyl (CAS 1809168-63-5)
- 1-Bromo-4-(2-fluorophenyl)benzene (CAS 40641-63-2)
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- 2-Bromo-4'-fluoro-1,1'-biphenyl (CAS 89346-54-3)
- 3-Bromo-3'-fluoro-1,1'-biphenyl (CAS 844856-60-6)
- 4'-Bromo-3-fluoro-1,1'-biphenyl (CAS 40641-65-4)
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