5-(5-Chloro-1,2,4-thiadiazol-3-yl)thiophene-2-sulfonyl chloride CAS 306937-21-3

Purity 97%+In StockPharmaceutical Standards
CAS No.306937-21-3
Molecular FormulaC6H2Cl2N2O2S3
Molecular Weight301.19 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-(5-Chloro-1,2,4-thiadiazol-3-yl)thiophene-2-sulfonyl chloride CAS 306937-21-3 chemical structure

Description

5-(5-Chloro-1,2,4-thiadiazol-3-yl)thiophene-2-sulfonyl chloride (CAS 306937-21-3) is a high-purity analytical reference standard with the molecular formula C6H2Cl2N2O2S3 and a molecular weight of 301.19 g/mol.

Based on its molecular formula C6H2Cl2N2O2S3, 5-(5-Chloro-1,2,4-thiadiazol-3-yl)thiophene-2-sulfonyl chloride contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 301.19 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-(5-Chloro-1,2,4-thiadiazol-3-yl)thiophene-2-sulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC6H2Cl2N2O2S3
Molecular Weight301.19 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl-containing
Nitrogen Atoms2
Sulfur Atoms3

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