N-[(1E)-1-{N'-[(1Z)-(4-fluorophenyl)methylidene]hydrazinecarbonyl}-2-[(4-methylpyrimidin-2-yl)amino]eth-1-en-1-yl]benzamide CAS 306976-33-0
| CAS No. | 306976-33-0 |
| Molecular Formula | C22H19FN6O2 |
| Molecular Weight | 418.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-[(1E)-1-{N'-[(1Z)-(4-fluorophenyl)methylidene]hydrazinecarbonyl}-2-[(4-methylpyrimidin-2-yl)amino]eth-1-en-1-yl]benzamide.
CATO supplies N-[(1E)-1-{N'-[(1Z)-(4-fluorophenyl)methylidene]hydrazinecarbonyl}-2-[(4-methylpyrimidin-2-yl)amino]eth-1-en-1-yl]benzamide (CAS 306976-33-0), a certified reference material (molecular formula C22H19FN6O2, MW 418.42 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, N-[(1E)-1-{N'-[(1Z)-(4-fluorophenyl)methylidene]hydrazinecarbonyl}-2-[(4-methylpyrimidin-2-yl)amino]eth-1-en-1-yl]benzamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 418.42 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H19FN6O2 |
| Molecular Weight | 418.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 6 |
Recommended Standards
- 4-Piperidinecarboxamide, 4-amino-1-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-n-[[4-(trifluoromethyl)phenyl]methyl]- (CAS 885500-14-1)
- Apremilast impurity 18 (CAS 1384439-79-5)
- 1-[6-[3-(3-methyldiazirin-3-yl)propanoylamino]hexanoyloxy]-2,5-dioxo-pyrrolidine-3-sulfonic acid (CAS 1909307-61-4)
- N1,N3-bis(4-((difluoromethyl)thio)phenyl)malonamide (CAS 1353504-43-4)
- (1-(Pyridin-3-ylmethyl)pyrrolidin-3-yl)methanamine (CAS 933749-39-4)
- 2-Methoxy-6-(2-naphthalen-2-yl-ethyl)-benzoic acid isopropyl ester (CAS 1171921-61-1)
- Ethyl 1,5-dimethyl-1H-imidazole-2-carboxylate (CAS 898834-10-1)
- 2-(1,3-Dioxolan-2-yl)-1-(4-isopropoxyphenyl)ethan-1-one (CAS 1263366-09-1)
- Tert-butyl (3-(cyanomethoxy)phenyl)carbamate (CAS 1099683-75-6)
- N1-(2,5-dimethylbenzyl)propane-1,3-diamine (CAS 953072-27-0)
- N-Boc-1-allyl-1-aminocyclooctane (CAS 1335042-78-8)
- Ticagrelor Impurity 47 (CAS 376608-74-1)
- 1-(2-Iodophenoxy)propan-2-one (CAS 871565-59-2)
- 103244-41-3 Insulin-like Growth Factor-II fragment 33-40 Ser-Arg-Val-Ser-Arg-Arg-Ser-Arg (CAS 103244-41-3)
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