3'-Chloro-4-(piperidin-1-yl)-5'-(trifluoromethyl)-3,6-dihydro-2H-1,2'-bipyridine CAS 306977-24-2
| CAS No. | 306977-24-2 |
| Molecular Formula | C16H19ClF3N3 |
| Molecular Weight | 345.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 3'-Chloro-4-(piperidin-1-yl)-5'-(trifluoromethyl)-3,6-dihydro-2H-1,2'-bipyridine (CAS 306977-24-2), a certified reference material (molecular formula C16H19ClF3N3, MW 345.79 g/mol) for analytical method development and quality control.
The molecular framework of 3'-Chloro-4-(piperidin-1-yl)-5'-(trifluoromethyl)-3,6-dihydro-2H-1,2'-bipyridine (C16H19ClF3N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3'-Chloro-4-(piperidin-1-yl)-5'-(trifluoromethyl)-3,6-dihydro-2H-1,2'-bipyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H19ClF3N3 |
| Molecular Weight | 345.79 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
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Recommended Standards
- 2-[(Adamantan-1-yl)methoxy]-3-chloro-5-(trifluoromethyl)pyridine (CAS 339098-66-7)
- N-(6-((2-Chlorobenzyl)thio)pyridazin-3-yl)furan-2-carboxamide (CAS 1021107-22-1)
- Lornoxicam Impurity 108 (CAS CATO-C4X-2016108)
- N-(4-chloro-3-nitrophenyl)-2-(3,4-dihydroquinolin-1(2H)-yl)acetamide (CAS 882079-80-3)
- N-(2-((2-(2-Fluorophenoxy)pyrimidin-5-yl)amino)-2-oxoethyl)benzamide (CAS 1421524-55-1)
- 2-(1H-1,2,3-Triazol-5-yl)ethanamine dihydrochloride (CAS 1225591-25-2)
- 1,4-Dihydro-3H-2-benzopyran-3-one 1H-2-Benzopyran-3(4H)-one 2-Hydroxymethylphenylacetic acid lactone 3,6-Dihydro-4,5-benzo-2-pyrone 3-Isochromanone 4385-35-7 (CAS 4385-35-7)
- Trihexyl Borate (CAS 5337-36-0)
- POE (1) C 18-24 tert-amine (CAS 73138-27-9)
- 4-Chloro-5-iodo-2-(trifluoromethyl)quinazoline (CAS 959237-72-0)
- 1-(3-Phenyl-1,2,4-oxadiazol-5-yl)cyclohexan-1-amine hydrochloride (CAS 1239785-99-9)
- 3-Methyltridecanoic acid (CAS 58054-74-3)
- Methyl 2-(4,6-Dimethoxypyrimidin-2-yl)cyclohexanoate (CAS 870083-40-2)
- [14-31]-Semaglutide (CAS CATO-C4X-2226262)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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