2-Chloro-6-(4-methoxyphenyl)nicotinonitrile CAS 306977-91-3
| CAS No. | 306977-91-3 |
| Molecular Formula | C13H9ClN2O |
| Molecular Weight | 244.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Chloro-6-(4-methoxyphenyl)nicotinonitrile (C13H9ClN2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2-Chloro-6-(4-methoxyphenyl)nicotinonitrile (CAS 306977-91-3) is a high-purity analytical reference standard with the molecular formula C13H9ClN2O and a molecular weight of 244.68 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Chloro-6-(4-methoxyphenyl)nicotinonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H9ClN2O |
| Molecular Weight | 244.68 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- 2-Chloro-4-(4-methoxyphenyl)nicotinonitrile (CAS 203803-04-7)
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- 8-Mercapto-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione (CAS 1784-70-9)
- 2-(Hydroxymethyl)-5-(methylsulfonyl)benzoic acid (CAS 2301882-90-4)
- Peptide Impurity 24 (CAS CATO-CPTD788824)
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