5-Acetyl-2-((4-chlorobenzyl)amino)-6-methylnicotinonitrile CAS 306980-05-2
| CAS No. | 306980-05-2 |
| Molecular Formula | C16H14ClN3O |
| Molecular Weight | 299.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 299.75 g/mol gives 5-Acetyl-2-((4-chlorobenzyl)amino)-6-methylnicotinonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-Acetyl-2-((4-chlorobenzyl)amino)-6-methylnicotinonitrile (CAS 306980-05-2) is a high-purity analytical reference standard with the molecular formula C16H14ClN3O and a molecular weight of 299.75 g/mol.
The molecular framework of 5-Acetyl-2-((4-chlorobenzyl)amino)-6-methylnicotinonitrile (C16H14ClN3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-Acetyl-2-((4-chlorobenzyl)amino)-6-methylnicotinonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H14ClN3O |
| Molecular Weight | 299.75 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Acetyl Standards
- [1-(4-Chlorobenzyl)-1H-indol-3-yl]acetic acid (CAS 219544-52-2)
- 2-(4-Chlorobenzyl)-5-methyl-4-phenyl-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 860789-80-6)
- 4-(4-Chlorobenzyl)-6-methoxyisoquinolin-7-ol (CAS 80143-63-1)
- Methyl 1-(4-chlorobenzyl)-1H-indole-2-carboxylate (CAS 860611-52-5)
- 3-((3-Chlorobenzyl)oxy)benzo[b]thiophene-2-carbonitrile (CAS 320422-45-5)
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- 4-(((4-Chlorobenzyl)sulfonyl)methyl)-3,5-dimethylisoxazole (CAS 303985-23-1)
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Recommended Standards
- 5-[(4-Chloro-2-methylphenoxy)methyl]-3-phenyl-1,2-oxazole (CAS 478066-25-0)
- 5-Chloro-N-(3-morpholinopropyl)-2-nitroaniline (CAS 330177-70-3)
- 4-Chlorophenethyl indolizine-7-carboxylate (CAS 62103-40-6)
- 6-Chloro-2-(4-methoxyphenyl)-5-methyl-1H-indole-3-carbaldehyde (CAS 920514-81-4)
- Neuropeptide AF (human) (CAS 192387-38-5)
- 3-methyl-2-oxo-pyrrolidine-3-carboxylic acid (CAS 1514072-02-6)
- Ethyl 5-methylpyrimidine-2-carboxylate (CAS 142730-00-5)
- 2-[(2-Chlorobenzyl)amino]benzoic acid (CAS 5363-30-4)
- 2-Hydroxy-5-(3-((3-methylthiophen-2-yl)methyl)ureido)benzoic acid (CAS 1540847-46-8)
- 2-(p-Hydroxyphenyl)-2-phenyl-acetophenone (CAS 5543-98-6)
- Iopromide impurity 14 (CAS CATO-C4X-183214)
- 4-(4-Iodophenyl)tetrahydro-2H-pyran (CAS 1434128-30-9)
- (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(o-tolyl)acetic acid (CAS 1260591-15-8)
- Insulin Degludec Impurity 10 (CAS CATO-C4X-215710)
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