3,4-Dichloro-N-[(E)-2-[6-methyl-3-(methylsulfanyl)-1,2,4-triazin-5-yl]ethenyl]aniline CAS 306980-29-0
| CAS No. | 306980-29-0 |
| Molecular Formula | C13H12Cl2N4S |
| Molecular Weight | 327.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3,4-Dichloro-N-[(E)-2-[6-methyl-3-(methylsulfanyl)-1,2,4-triazin-5-yl]ethenyl]aniline (CAS 306980-29-0) is a high-purity analytical reference standard with the molecular formula C13H12Cl2N4S and a molecular weight of 327.23 g/mol.
The molecular framework of 3,4-Dichloro-N-[(E)-2-[6-methyl-3-(methylsulfanyl)-1,2,4-triazin-5-yl]ethenyl]aniline (C13H12Cl2N4S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H12Cl2N4S |
| Molecular Weight | 327.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Dichloro Standards
- (E)-3,5-dichloro-N-(2-(6-methyl-3-(methylthio)-1,2,4-triazin-5-yl)vinyl)aniline (CAS 400077-33-0)
- 4,6-Dichloro-5-(2-phenyldiazenyl)-2-(propylthio)pyrimidine (CAS 946855-77-2)
- 2-(2,7-Dichloro-9H-carbazol-9-yl)aniline (CAS 922517-42-8)
- 2,6-Dichloro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1227266-90-1)
- 4,6-Dichloro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1227267-08-4)
- 5,7-Dichloro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-c]pyridine (CAS 1227270-60-1)
- 4-(2,4-Dichloro-benzyloxy)-3-methoxy-benzoic acid (CAS 113457-31-1)
- Methyl 2-(1,1-dichloro-4-oxo-1,1a,2,3,4,8b-hexahydrobenzo[a]cyclopropa[c][7]annulen-3-yl)-2-oxoacetate (CAS 2055840-43-0)
Recommended Standards
- 2-[(2-Aminophenyl)sulfanyl]-N-(2,4-dichlorophenyl)acetamide (CAS 92291-38-8)
- 2,2-Dimethyl-1-(7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indol-1-yl)propan-1-one (CAS 2376879-92-2)
- Methyl 2-((2,4-dichlorobenzyl)thio)benzoate (CAS 308851-38-9)
- 2,2-Dimethyl-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indol-3-yl)propan-1-one (CAS 2390149-33-2)
- 4-Bromobenzoic anhydride (CAS 1633-33-6)
- tert-butyl (2R,4R)-4-azido-2-(hydroxymethyl)pyrrolidine-1-carboxylate (CAS 1161931-70-9)
- 1-(3,5-Difluorobenzyl)-1H-pyrazol-4-ol (CAS 1600473-20-8)
- 2-(Boc-amino)-4-bromo-5-formylthiazole (CAS 944805-17-8)
- (S)-3-Isopropyl-5-(4-(1-((5-(4-(methylsulfonyl)phenyl)pyrazin-2-yl)oxy)ethyl)piperidin-1-yl)-1,2,4-oxadiazole (CAS 1032824-43-3)
- 4-(4-Bromophenyl)-2-chloro-7,8-dihydro-5H-pyrano[4,3-b]pyridine-3-carbonitrile (CAS 1708251-15-3)
- 8-Azaspiro[bicyclo[3.2.1]Octane-3,4'-imidazolidine]-2',5'-dione (CAS 77699-15-1)
- (3AR,5aR,8aR,8bS)-3a-(iodomethyl)-2,2,7,7-tetramethyltetrahydro-5H-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran (CAS 38084-03-6)
- 3,6-Difluoro-2-methoxybenzonitrile (CAS 1010413-52-1)
- Semaglutide impurity 49 (CAS CATO-C4X-222649)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com