4-(2-Ethoxyphenoxy)-2-methylaniline CAS 307308-58-3
| CAS No. | 307308-58-3 |
| Molecular Formula | C15H17NO2 |
| Molecular Weight | 243.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-(2-Ethoxyphenoxy)-2-methylaniline (CAS 307308-58-3) is a high-purity analytical reference standard with the molecular formula C15H17NO2 and a molecular weight of 243.30 g/mol.
Structurally, 4-(2-Ethoxyphenoxy)-2-methylaniline (C15H17NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 243.30 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 4-(2-Ethoxyphenoxy)-2-methylaniline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H17NO2 |
| Molecular Weight | 243.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 1 |
Related Ethoxyphenoxy Standards
- 3-[(4-ethoxyphenoxy)methyl]aniline (CAS 1016729-14-8)
- 2-(2-Ethoxyphenoxy)-4-methylaniline (CAS 946774-21-6)
- 2-(2-Ethoxyphenoxy)-5-methylaniline (CAS 946682-90-2)
- 2-(3-Ethoxyphenoxy)-4-methylaniline (CAS 946716-66-1)
- 2-(3-Ethoxyphenoxy)-5-methylaniline (CAS 946728-65-0)
- 2-(4-Ethoxyphenoxy)-4-methylaniline (CAS 946774-49-8)
- 2-(4-Ethoxyphenoxy)-5-methylaniline (CAS 946728-53-6)
- 4-(2-Ethoxyphenoxy)-3-methylaniline (CAS 946663-52-1)
Recommended Standards
- 4-(2-Aminoethyl)-5-cyclopropyl-2-phenyl-1H-pyrazol-3(2H)-one (CAS 952958-77-9)
- 4-(2-(Benzyloxy)ethoxy)aniline (CAS 726196-87-8)
- 4-(2-Methoxy-4-methylphenoxy)-2-methylphenylamine (CAS 946786-32-9)
- 4-(1H-indol-3-yl)piperidine-1-carboxamide (CAS 929975-37-1)
- Isodonoiol (CAS 82460-75-1)
- Methyl 1-(2-(cyclopentylamino)-2-oxoethyl)-3-cyclopropyl-6-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1018052-47-5)
- 3-(2-Methoxyphenyl)-1,2,4-oxadiazole-5-carbaldehyde (CAS 944901-99-9)
- 6-Ethoxy-N-(pyridin-2-ylmethyl)-1,3-benzothiazol-2-amine (CAS 1105194-96-4)
- Empagliflozin Impurity 118 (CAS CATO-C4X-1065118)
- 1-tert-Butyl 3-methyl 4-methylpiperidine-1,3-dicarboxylate (CAS 1201192-62-2)
- 2-Fluoro-N-(4-iodophenyl)benzamide (CAS 304882-39-1)
- 1-Methyl-2-(methylthio)-4-nitro-1H-imidazole (CAS 86072-16-4)
- Ethyl 4-(cyclopropylamino)-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate (CAS 1044909-25-2)
- Semaglutide Impurity 163 (x TFA Salt) (CAS CATO-C4X-2226163)
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