4-(2,6-Difluorophenoxy)aniline CAS 307308-81-2
| CAS No. | 307308-81-2 |
| Molecular Formula | C12H9F2NO |
| Molecular Weight | 221.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-(2,6-Difluorophenoxy)aniline (CAS 307308-81-2) is a high-purity analytical reference standard with the molecular formula C12H9F2NO and a molecular weight of 221.20 g/mol.
Based on its molecular formula C12H9F2NO, 4-(2,6-Difluorophenoxy)aniline contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 221.20 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 4-(2,6-Difluorophenoxy)aniline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H9F2NO |
| Molecular Weight | 221.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluorophenoxy Standards
- 2-(3,5-Difluorophenoxy)aniline (CAS 1341725-06-1)
- 2-(2,4-Difluorophenoxy)aniline (CAS 187845-72-3)
- 2-(3,4-Difluorophenoxy)aniline (CAS 640766-59-2)
- 3-(2,3-Difluorophenoxy)aniline (CAS 887580-81-6)
- 3-(3,5-Difluorophenoxy)aniline (CAS 887580-88-3)
- 4-(2,4-Difluorophenoxy)aniline (CAS 286932-63-6)
- 4-(3,4-Difluorophenoxy)aniline (CAS 383126-84-9)
- 4-(3,5-Difluorophenoxy)aniline (CAS 307308-83-4)
Recommended Standards
- 3-Fluoro-4-(4-fluorophenoxy)aniline (CAS 937597-91-6)
- 3-Fluoro-4-(3-fluorophenoxy)aniline (CAS 937597-93-8)
- 4-(TrifluoroMethylthio)benzaMide (CAS 330-15-4)
- 3-Fluoro-4-(2-fluorophenoxy)aniline (CAS 946699-01-0)
- 5-(4-Methylphenyl)-1H-pyrrolo[1,2-c][1,3]thiazole-6,7-dicarboxylic acid (CAS 860609-33-2)
- (R,R)-2-Bn-Sabox-Bn (CAS 2634687-70-8)
- 5-Oxohexanoic Acid (CAS 3128-06-1)
- Methyl 5-(dipropylcarbamoyl)-2-(4-fluorobenzamido)-4-methylthiophene-3-carboxylate (CAS 335405-83-9)
- 2-((4-Oxo-3-phenyl-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetohydrazide (CAS 144316-16-5)
- Toltrazuril Impurity 2 (CAS 94155-78-9)
- (R)-N-(3-(1-Hydroxyethyl)phenyl)acetamide (CAS 1344956-10-0)
- Ethyl 2-Oxo-5-phenyl-2,3-dihydro-1H-imidazole-4-carboxylate (CAS 92809-78-4)
- 4-((4-Fluorophenyl)imino)pent-2-en-2-ol (CAS 88556-44-9)
- Cyclolinopeptide B (CAS 193139-41-2)
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