2-Methyl-5-(morpholinomethyl)furan-3-carboxylic acid CAS 309271-37-2
| CAS No. | 309271-37-2 |
| Molecular Formula | C11H15NO4 |
| Molecular Weight | 225.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-Methyl-5-(morpholinomethyl)furan-3-carboxylic acid (CAS 309271-37-2) is a high-purity analytical reference standard with the molecular formula C11H15NO4 and a molecular weight of 225.24 g/mol.
The molecular framework of 2-Methyl-5-(morpholinomethyl)furan-3-carboxylic acid (C11H15NO4) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H15NO4 |
| Molecular Weight | 225.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 1 |
Related Methyl Standards
- 1-Methyl-5-(morpholinomethyl)-1H-pyrazole-3-carboxylic acid (CAS 1198439-06-3)
- 5-Methyl-4-(morpholinomethyl)furan-2-carboxylic acid (CAS 26095-39-6)
- 6-Methyl-5-(morpholinomethyl)pyrimidine-2,4(1H,3H)-dione (CAS 23213-33-4)
- Methyl 5-(morpholinomethyl)furan-2-carboxylate (CAS 26095-04-5)
- 1-(4-(Morpholinomethyl)thiophen-2-yl)ethan-1-one (CAS 924852-23-3)
- 5-Methyl-4-(morpholinomethyl)thiophene-2-carbaldehyde (CAS 889973-56-2)
- (5-(Morpholinomethyl)thiophen-2-yl)boronic acid (CAS 1142947-90-7)
- (5-(Morpholinomethyl)thiophen-3-yl)boronic acid (CAS 1345956-76-4)
Recommended Standards
- 2-Methoxyacridin-9(10H)-one (CAS 49742-72-5)
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- 2-Phenyl-2H-benzo[e][1,3]oxazin-4(3H)-one (CAS 6629-80-7)
- 2-((2-Chlorobenzyl)amino)-2-oxoethyl 5-bromofuran-2-carboxylate (CAS 386277-36-7)
- 7-Fluoroquinoline-3-carbonitrile (CAS 352521-51-8)
- 5-(4-(5,5-Dimethyl-1,3,2-dioxaborinane)phenyl) dipyrromethane (CAS 1025707-99-6)
- Sarizotan Impurity 9 (CAS 177976-39-5)
- 2-(1-Methyl-1,4,6,7-tetrahydropyrano[4,3-c]pyrazol-4-yl)acetic acid (CAS 1421604-50-3)
- 8-(2-Methoxy-4-(methylsulfinyl)phenyl)-1H-purine (CAS 77456-53-2)
- (4-Chlorophenyl)methyl N-[(E)-2-(2-chlorophenyl)ethenyl]carbamate (CAS 338413-45-9)
- 2-Amino-5-(4-bromophenyl)-5-[(4-methoxyphenyl)methyl]-4,5-dihydro-1H-imidazol-4-one (CAS 1354918-10-7)
- Bis(2-n-butoxyethyl)sebacate (CAS 141-19-5)
- Insulin Degludec Impurity 3 (CAS CATO-C4X-21573)
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