methyl (3R)-3-amino-3-(3-iodophenyl)propanoate CAS 309757-74-2
| CAS No. | 309757-74-2 |
| Molecular Formula | C10H12INO2 |
| Molecular Weight | 305.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including methyl (3R)-3-amino-3-(3-iodophenyl)propanoate.
methyl (3R)-3-amino-3-(3-iodophenyl)propanoate (CAS 309757-74-2) is a high-purity analytical reference standard with the molecular formula C10H12INO2 and a molecular weight of 305.11 g/mol.
The molecular framework of methyl (3R)-3-amino-3-(3-iodophenyl)propanoate (C10H12INO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), methyl (3R)-3-amino-3-(3-iodophenyl)propanoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H12INO2 |
| Molecular Weight | 305.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- Ethyl 6-amino-2-iodo-3-methylbenzoate (CAS 2091227-59-5)
- Methyl 2-amino-4-ethyl-5-iodobenzoate (CAS 912575-12-3)
- Ethyl 2-amino-5-iodo-3-methylbenzoate (CAS 908005-99-2)
- Methyl 4-(dimethylamino)-3-iodobenzoate (CAS 99067-73-9)
- 3-(Morpholinomethyl)benzothioamide (CAS 1016836-55-7)
- tert-Butyl 4-(benzo[d]isothiazol-3-ylamino)piperidine-1-carboxylate (CAS 1002355-72-7)
- tert-Butyl 3-(Chloromethyl)benzoate (CAS 220510-74-7)
- N-(3-Ethoxybenzyl)-3-(2-phenoxyethoxy)aniline (CAS 1040686-39-2)
- Ethyl 4-hydroxy-3-methylbenzo[b]thiophene-6-carboxylate (CAS 955886-74-5)
- N-ethyl-N-methylpyrrolidin-3-amine dihydrochloride (CAS 1803607-79-5)
- 2-bromo-1-(4-bromo-3-fluoro-phenyl)ethanone (CAS 1003879-02-4)
- Fmoc-D-Cys(Trt)-OH (CAS 167015-11-4)
- N-(Isobutyryloxy)-2-(quinolin-8-yloxy)acetimidamide (CAS 88758-60-5)
- Cholecystokinin Octapeptide (1-3) (desulfated) H-Asp-Tyr-Met-OH (CAS 121880-94-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com