4,4'-Sulfonylbis(methoxybenzene) CAS 3112-80-9
| CAS No. | 3112-80-9 |
| Molecular Formula | C14H14O4S |
| Molecular Weight | 278.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4,4'-Sulfonylbis(methoxybenzene).
CATO supplies 4,4'-Sulfonylbis(methoxybenzene) (CAS 3112-80-9), a certified reference material (molecular formula C14H14O4S, MW 278.32 g/mol) for analytical method development and quality control.
The molecular framework of 4,4'-Sulfonylbis(methoxybenzene) (C14H14O4S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4,4'-Sulfonylbis(methoxybenzene) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H14O4S |
| Molecular Weight | 278.32 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Sulfur Atoms | 1 |
Related Sulfonylbis Standards
- 4,4'-Sulfonylbis(benzene-1,2-diamine) (CAS 13224-79-8)
- (Sulfonylbis(3,1-phenylene))bis(hydrazine) (CAS 443292-88-4)
- 4,4'-Sulfonylbis(N-methylaniline) (CAS 7324-96-1)
- 4,4'-Sulfonylbis(1,2-dimethylbenzene) (CAS 28361-43-5)
- 4,4′-Sulfonylbis(2-methylphenol) (CAS 16346-97-7)
- 1,1′-Sulfonylbis[octane] (CAS 7726-20-7)
- 2,2'-Sulfonylbis(1,3,5-trimethylbenzene) (CAS 3112-79-6)
- 4,4'-Sulfonylbis(tert-butylbenzene) (CAS 5453-70-3)
Recommended Standards
- 1-Fluoro-5-oxo-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl pivalate (CAS 2114341-48-7)
- 2-(Benzyloxy)-5-fluoro-1,1'-biphenyl (CAS 2624417-57-6)
- 1-(4-Fluorophenyl)-3-[(4-fluorophenyl)sulfanyl]propan-1-one (CAS 477334-43-3)
- 2-(tert-Butoxycarbonyl)benzo[b]thiophene-5-carboxylic acid (CAS 2502300-24-3)
- (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(2,3-dimethoxyphenyl)propanoic acid (CAS 1260604-86-1)
- 4-Bromo-2-(3,3-difluoroazetidin-1-yl)pyridine (CAS 1707604-97-4)
- 5-methoxy-3,3-dimethyl-2,3-dihydro-1H-inden-1-one (CAS 60812-53-5)
- (S)-1-phenethylpyrrolidin-3-amine (CAS 267643-79-8)
- 1-Cyclopropylprop-2-en-1-amine (CAS 1160786-00-4)
- n-(3-Aminopropyl)-2-fluorobenzamide (CAS 1016795-79-1)
- methyl 3-(cyanomethyl)-4-nitrobenzoate (CAS 1260763-08-3)
- 1,1-Difluoro-5-azaspiro[2.5]octane (CAS 1393559-49-3)
- 2-Butenedioic acid (2E)-, polymer with 1,3-butadiene and 2-propenenitrile (CAS 33827-49-5)
- Endo-Pro36-Tirzepatide (CAS CATO-CPTD788688)
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