2-Chloro-4-(o-carboxyphenylamino)pyrimidine CAS 31185-80-5
| CAS No. | 31185-80-5 |
| Molecular Formula | C11H8ClN3O2 |
| Molecular Weight | 249.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-4-(o-carboxyphenylamino)pyrimidine.
2-Chloro-4-(o-carboxyphenylamino)pyrimidine (CAS 31185-80-5) is a high-purity analytical reference standard with the molecular formula C11H8ClN3O2 and a molecular weight of 249.65 g/mol.
Structurally, 2-Chloro-4-(o-carboxyphenylamino)pyrimidine (C11H8ClN3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 249.65 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-Chloro-4-(o-carboxyphenylamino)pyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H8ClN3O2 |
| Molecular Weight | 249.65 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 3-Chloro-6-(4-methyl-3-nitrophenyl)pyridazine (CAS 1030584-84-9)
- 4-Chloro-6-methyl-2-(4-nitrophenyl)pyrimidine (CAS 1153408-91-3)
- 2-Chloro-5-(pyrimidin-2-ylamino)benzoic acid (CAS 1184378-11-7)
- 5-Chloro-2-phenoxynicotinic acid (CAS 1189749-38-9)
- 2-Chloro-6-methyl-5-nitro-3,3'-bipyridine (CAS 1214352-55-2)
- 6-Chloro-4-methyl-5-nitro-3,4'-bipyridine (CAS 1214371-42-2)
- 6-Chloro-2-methyl-5-nitro-3,4'-bipyridine (CAS 1214377-62-4)
- 2-Chloro-6-methyl-5-nitro-3,4'-bipyridine (CAS 1214387-21-9)
Recommended Standards
- 2-Chloro-3-formylquinolin-7-yl acetate (CAS 745830-14-2)
- 2-Chloro-4-nitro-1-phenoxybenzene (CAS 56966-69-9)
- 2-(4-Chlorophenyl)-5-(2-nitrovinyl)furan (CAS 56297-21-3)
- 2-Chlorophenyl-4'-nitrophenyl ether (CAS 2091-61-4)
- 2-((5-Bromo-4-chloro-1H-indol-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (CAS 1174456-59-7)
- Ethyl 1-methyl-4-oxo-1,4-dihydroquinoline-2-carboxylate (CAS 60442-66-2)
- 2-methylpiperidine (CAS 109-05-7)
- 2-(1H-Pyrrol-1-yl)benzoyl chloride (CAS 133662-28-9)
- 2-{[2-(4-methylphenyl)-1h-indol-3-yl]sulfanyl}ethan-1-amine (CAS 865546-52-7)
- 4-(Butoxycarbonyl)phenyl 4-chlorobenzoate (CAS 331462-13-6)
- N,N-Diethylacetamide (CAS 685-91-6)
- methyl N-[2-chloro-4-(chlorosulfonyl)phenyl]carbamate (CAS 1599787-03-7)
- Methazolamide Impurity 3 (CAS CATO-C4X-34043)
- Semaglutide impurity 75 (CAS CATO-C4X-222675)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com