4-[(4-chloro-3-nitro-1h-pyrazol-1-yl)methyl]benzoic acid CAS 312601-70-0
| CAS No. | 312601-70-0 |
| Molecular Formula | C11H8ClN3O4 |
| Molecular Weight | 281.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 4-[(4-chloro-3-nitro-1h-pyrazol-1-yl)methyl]benzoic acid (CAS 312601-70-0), a certified reference material (molecular formula C11H8ClN3O4, MW 281.65 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 4-[(4-chloro-3-nitro-1h-pyrazol-1-yl)methyl]benzoic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 281.65 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H8ClN3O4 |
| Molecular Weight | 281.65 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related chloro Standards
- 1-[(4-chloro-3-nitrophenyl)methyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione (CAS 1097789-53-1)
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- 2-Chloro-5-methoxy-4-(3-nitrophenoxy)pyrimidine (CAS 1643967-59-2)
- 2-Chloro-N-(5-methylisoxazol-3-yl)-5-nitrobenzamide (CAS 313223-89-1)
- 3-((4-Chloro-3-nitro-1h-pyrazol-1-yl)methyl)benzoic acid (CAS 402720-00-7)
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Recommended Standards
- 5-((2-Nitrophenoxy)methyl)furan-2-carbonyl chloride (CAS 861439-34-1)
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- 1-(4-Chlorobenzyl)-3-nitro-1H-pyrazole-5-carboxylic acid (CAS 402614-96-4)
- 5-(Carboxymethyl)-1-(4-chlorophenyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 439095-10-0)
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- 6-(4-Phenylpiperazin-1-yl)pyridazin-3-ol (CAS 362661-29-8)
- (3-((4-Fluorobenzyl)amino)phenyl)methanol (CAS 1152696-00-8)
- O-Benzyl-DL-serine (CAS 5445-44-3)
- (R)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-2-(2,3-dimethoxybenzyl)propanoic acid (CAS 1260591-77-2)
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