N-(4-Acetylphenyl)-3-fluorobenzamide CAS 312703-73-4
| CAS No. | 312703-73-4 |
| Molecular Formula | C15H12FNO2 |
| Molecular Weight | 257.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-(4-Acetylphenyl)-3-fluorobenzamide (CAS 312703-73-4), molecular formula C15H12FNO2 and molecular weight 257.26 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, N-(4-Acetylphenyl)-3-fluorobenzamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 257.26 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(4-Acetylphenyl)-3-fluorobenzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H12FNO2 |
| Molecular Weight | 257.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related N Standards
- N-(3-acetylphenyl)-3-fluorobenzamide (CAS 194783-81-8)
- N-(3-Acetylphenyl)-4-fluorobenzamide (CAS 194783-82-9)
- ((3-Acetylphenyl)sulfonyl)glycine (CAS 790270-98-3)
- {[(4-acetylphenyl)sulfonyl]amino}acetic acid (CAS 749920-47-6)
- N-(3-acetylphenyl)-2-fluorobenzamide (CAS 303091-99-8)
- N-(4-acetylphenyl)-2-fluorobenzamide (CAS 303091-98-7)
- n-(4-Acetylphenyl)-4-fluorobenzamide (CAS 300668-14-8)
- 5-(4-Acetylphenyl)-2-hydroxyisonicotinic acid (CAS 1261921-02-1)
Recommended Standards
- 1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl methanesulfonate (CAS 1246012-56-5)
- Daidzein-3',5',8-d3 (CAS 220930-96-1)
- Linezolid Impurity 34 (CAS CATO-C4X-107334)
- 6-Sulfamoyl-3,4-dihydro-2h-1-benzopyran-3-carboxylic acid (CAS 885532-14-9)
- 2-(2-Cyclohexenyl)-4-methylpyridine (CAS 1187168-47-3)
- (R)-Piperidine-2-carboxamide (CAS 78088-51-4)
- N-(5-Amino-2-fluorophenyl)-3-isobutoxybenzamide (CAS 1020055-53-1)
- (3,4-Dihydro-2H-pyran-2-yl)methyl 3,4-dihydro-2H-pyran-2-carboxylate (CAS 3540-36-1)
- Ethyl 3-(phenylthio)-1H-indole-2-carboxylate (CAS 106184-17-2)
- 4-(2-Methoxyethyl)-5-(4-nitrophenyl)-4H-1,2,4-triazole-3-thiol (CAS 917747-82-1)
- 6-Phenyl-6,7-dihydro-3H-pyrrolo[3,4-d]pyrimidin-4(5H)-one (CAS 23935-84-4)
- 5-Methoxybenzimidazole (CAS 4887-80-3)
- n-((1,2,3-Thiadiazol-4-yl)methyl)cyclopropanamine (CAS 1156892-42-0)
- Tirzepatide Impurity 20 (CAS CATO-C4X-324020)
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