N-(3-acetylphenyl)-5-chlorothiophene-2-carboxamide CAS 312772-68-2

Purity 97%+In StockPharmaceutical Standards
CAS No.312772-68-2
Molecular FormulaC13H10ClNO2S
Molecular Weight279.74 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(3-acetylphenyl)-5-chlorothiophene-2-carboxamide CAS 312772-68-2 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 279.74 g/mol gives N-(3-acetylphenyl)-5-chlorothiophene-2-carboxamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

N-(3-acetylphenyl)-5-chlorothiophene-2-carboxamide (CAS 312772-68-2), molecular formula C13H10ClNO2S and molecular weight 279.74 g/mol, is a CATO reference standard with documented purity and traceability.

N-(3-acetylphenyl)-5-chlorothiophene-2-carboxamide (C13H10ClNO2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures N-(3-acetylphenyl)-5-chlorothiophene-2-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC13H10ClNO2S
Molecular Weight279.74 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl-containing
Nitrogen Atoms1
Sulfur Atoms1

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