N-(2-Benzoyl-4-chlorophenyl)-3,4-difluorobenzamide CAS 312923-12-9
| CAS No. | 312923-12-9 |
| Molecular Formula | C20H12ClF2NO2 |
| Molecular Weight | 371.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), N-(2-Benzoyl-4-chlorophenyl)-3,4-difluorobenzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
N-(2-Benzoyl-4-chlorophenyl)-3,4-difluorobenzamide (CAS 312923-12-9), molecular formula C20H12ClF2NO2 and molecular weight 371.76 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N-(2-Benzoyl-4-chlorophenyl)-3,4-difluorobenzamide (C20H12ClF2NO2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H12ClF2NO2 |
| Molecular Weight | 371.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related N Standards
- N-(2-benzoyl-4-chlorophenyl)-2-chlorobenzamide (CAS 289059-82-1)
- N6-Benzoyl-2’-deoxy-2’-fluoroadenosine (CAS 136834-20-3)
- N6-Benzoyl-2'-fluoro-2'-deoxyarabinoadenosine (CAS 144924-99-2)
- 5-Benzoyl-2-(phenylamino)-4-(1H-pyrrol-1-yl)thiophene-3-carbonitrile (CAS 338966-44-2)
- Ethyl 3-benzoyl-2-phenylindolizine-1-carboxylate (CAS 102767-46-4)
- Ethyl 8-benzoyl-4,6-dichloro-3-quinolinecarboxylate (CAS 339099-41-1)
- 4-Benzoyl-1-[(3-fluorophenyl)methyl]-3-methyl-1,2,3,4-tetrahydroquinoxalin-2-one (CAS 317822-20-1)
- 2-Benzoyl-3-{[(4-methoxyphenyl)sulfanyl]methyl}-1-benzofuran (CAS 338424-56-9)
Recommended Standards
- 4-(4-Chlorophenyl)-5-(4-(trifluoromethoxy)phenyl)-4H-1,2,4-triazole-3-thiol (CAS 263707-20-6)
- (4-Methoxyphenyl)methyl N-(3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-yl)carbamate (CAS 477848-89-8)
- 4-(2-Chlorophenyl)-5-(4-(trifluoromethoxy)phenyl)-4H-1,2,4-triazole-3-thiol (CAS 263707-21-7)
- (5-Chloro-1-methyl-3-phenyl-1H-pyrazol-4-yl)methyl 4-nitrobenzoate (CAS 318234-22-9)
- 2-(2-Methyl-1,3-oxazol-4-yl)acetic acid (CAS 36042-28-1)
- 2-Amino-4-methoxybenzoic Acid (CAS 4294-95-5)
- 5-(4-Methyltetrahydro-2H-pyran-4-yl)pyridin-2-amine (CAS 1715031-48-3)
- 3-(Boc-amino)benzyl Alcohol (CAS 118684-31-4)
- 2-(Perfluorophenoxy)ethan-1-amine hydrochloride (CAS 1051368-88-7)
- ethyl N-[2-(aminomethyl)-1-(4-methoxyphenyl)-3-methylbutyl]carbamate (CAS 1808568-99-1)
- (1R,2S,3R,5S)-5-Acetyloxy-2-hydroxymethyl-3-tetrahydropyranyloxy-α-(phenylseleno)cyclopentaneheptanoic Acid Methyl Ester (Mixture of Diastereomers) (CAS 61302-47-4)
- 1-(2,4-Dichlorophenyl)-1H-pyrrole-2,5-dione (CAS 26396-57-6)
- 4-Bromomethylphenylboronic acid pinacol ester (CAS 138500-85-3)
- Semaglutide impurity 290 (CAS CATO-C4X-2226290)
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