6-Chloro-4-phenyl-2-(piperazin-1-yl)quinazoline CAS 313398-51-5
| CAS No. | 313398-51-5 |
| Molecular Formula | C18H17ClN4 |
| Molecular Weight | 324.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 324.81 g/mol gives 6-Chloro-4-phenyl-2-(piperazin-1-yl)quinazoline distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
6-Chloro-4-phenyl-2-(piperazin-1-yl)quinazoline (CAS 313398-51-5), molecular formula C18H17ClN4 and molecular weight 324.81 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 6-Chloro-4-phenyl-2-(piperazin-1-yl)quinazoline (C18H17ClN4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 6-Chloro-4-phenyl-2-(piperazin-1-yl)quinazoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H17ClN4 |
| Molecular Weight | 324.81 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
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Recommended Standards
- 5-(((2-(4-Chlorophenyl)oxazol-4-yl)methyl)thio)-1,3,4-thiadiazol-2-amine (CAS 792940-78-4)
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- 4-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]thiomorpholine-3,5-dione (CAS 338391-86-9)
- N-(benzo[d]thiazol-2-yl)-4-chlorobenzenesulfonamide (CAS 35607-93-3)
- 5-Bromo-6-phenylpyridin-2-ylamine (CAS 1308677-09-9)
- 6-Amino-2-cyclopropylpyrimidin-4-ol (CAS 954388-42-2)
- rel-(4aR,7aS)-tert-Butyl hexahydrofuro[3,4-b]pyrazine-1(2H)-carboxylate (CAS 1314393-75-3)
- 6,8-Dibromo-2-phenylquinoline-4-carboxylic acid (CAS 303793-47-7)
- N-(2-methoxyethyl)-N-methylazetidin-3-amine (CAS 759436-38-9)
- 4-(2-Bromobenzyl)thiomorpholine (CAS 414887-06-2)
- Methyl (S)-2-amino-4-bromobutanoate hydrobromide (CAS 101650-17-3)
- Tert-butyl 2-(hydroxydimethylsilyl)-1H-pyrrole-1-carboxylate (CAS 879904-82-2)
- (Methylsulfinyl)cyclopropane (CAS 79306-50-6)
- Peptide 440 (CAS CATO-CPTD788440)
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