2-((2-Chloropyridin-3-yl)oxy)ethan-1-ol CAS 313657-79-3
| CAS No. | 313657-79-3 |
| Molecular Formula | C7H8ClNO2 |
| Molecular Weight | 173.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-((2-Chloropyridin-3-yl)oxy)ethan-1-ol (CAS 313657-79-3), molecular formula C7H8ClNO2 and molecular weight 173.60 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-((2-Chloropyridin-3-yl)oxy)ethan-1-ol (C7H8ClNO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H8ClNO2 |
| Molecular Weight | 173.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloropyridin Standards
- 2-((6-Chloropyridin-2-yl)oxy)ethan-1-ol (CAS 104472-98-2)
- 2-[(2-chloropyridin-4-yl)oxy]ethan-1-ol (CAS 1934409-61-6)
- 1-(5-Chloropyridin-2-yl)ethane-1,2-diol (CAS 251661-02-6)
- 2-[(5-chloropyridin-3-yl)oxy]ethan-1-ol (CAS 223797-68-0)
- 3-(4-Chloropyridin-3-yl)prop-2-yn-1-ol (CAS 1203499-62-0)
- 2-((3-Chloropyridin-2-yl)oxy)ethan-1-amine (CAS 1249800-12-1)
- 2-((3-Chloropyridin-4-yl)oxy)ethan-1-amine (CAS 1505185-58-9)
- 2-((5-Chloropyridin-2-yl)oxy)ethan-1-amine (CAS 29450-00-8)
Recommended Standards
- 2-((2-Chloropyrimidin-4-yl)amino)ethan-1-ol (CAS 55662-06-1)
- 1-(3-Amino-5-methyl-1H-pyrazol-1-yl)-2-chloroethanone (CAS 453576-50-6)
- 2-((3-Chloropyrazin-2-yl)amino)ethan-1-ol (CAS 84066-20-6)
- (6-Chloro-5-methoxypyridin-3-yl)methanol (CAS 915107-47-0)
- 1,3,5-Tris(bromomethyl)-2,4,6-triethylbenzene (CAS 181058-08-2)
- 1-(Thiophen-2-ylmethyl)piperidine-4-carbaldehyde (CAS 926921-80-4)
- 4-Hydroxy-3-(2-hydroxy-2-methylpropyl)-1-methylquinolin-2(1H)-one (CAS 93574-06-2)
- methyl 3-(benzylamino)propanoate (CAS 23574-01-8)
- 4-Amino-n-(4-hydroxycyclohexyl)benzene-1-sulfonamide (CAS 174628-50-3)
- 1',3'-Dimethyl-1H,1'H-3,4'-bipyrazole (CAS 1006356-56-4)
- (4-Formyl-2,6-diiodophenoxy)acetonitrile (CAS 1226806-27-4)
- 3-Azetidinomethyl-2-methylbenzophenone (CAS 898771-19-2)
- 3-(Furan-2-ylmethyl)-4-methyl-2-((1-(thiophen-2-yl)ethylidene)hydrazineylidene)-2,3-dihydrothiazole (CAS 380317-58-8)
- Peptide Impurity 27 (CAS 1350456-68-6)
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