5-(4-Fluorophenyl)pyrimidin-2-amine CAS 31408-40-9
| CAS No. | 31408-40-9 |
| Molecular Formula | C10H8FN3 |
| Molecular Weight | 189.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(4-Fluorophenyl)pyrimidin-2-amine.
5-(4-Fluorophenyl)pyrimidin-2-amine (CAS 31408-40-9) is a high-purity analytical reference standard with the molecular formula C10H8FN3 and a molecular weight of 189.19 g/mol.
5-(4-Fluorophenyl)pyrimidin-2-amine (C10H8FN3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-(4-Fluorophenyl)pyrimidin-2-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H8FN3 |
| Molecular Weight | 189.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Fluorophenyl Standards
- 6-(4-Fluorophenyl)pyrimidin-4-amine (CAS 1036990-57-4)
- 6-(4-Fluorophenyl)pyridazin-3-amine (CAS 105538-07-6)
- 2-(3-fluorophenyl)pyrimidin-5-amine (CAS 1094411-86-5)
- 6-(4-Fluorophenyl)-2-hydroxypyridine (CAS 1111111-04-6)
- 6-(3-Fluorophenyl)pyridin-2-ol (CAS 1111114-86-3)
- 6-(4-Fluorophenyl)pyrazin-2-amine (CAS 1159815-52-7)
- 4-(3-Fluorophenyl)pyridin-2-ol (CAS 1159817-41-0)
- 4-(4-Fluorophenyl)pyridin-2(1H)-one (CAS 1159817-47-6)
Recommended Standards
- 5-(4-Fluorophenyl)pyridin-3-ol (CAS 364763-21-3)
- 5-(4-fluorophenyl)pyrimidin-4-amine (CAS 56239-05-5)
- 5-(4-Fluorophenyl)pyrazin-2-amine (CAS 69816-51-9)
- 5-(S-Methylsulfonimidoyl)furan-2-carboxylic acid (CAS 2773465-25-9)
- 1-(Bromoacetyl)indoline (CAS 73392-01-5)
- (S)-2-fluoro-7-(1-methoxyethyl)pyrazolo[1,5-a]pyrimidine-6-carboxylic acid (CAS 1832582-45-2)
- 4-[Tert-butyl(dimethyl)silyl]oxy-3-fluoro-cyclopent-2-en-1-one (CAS 113962-13-3)
- 2-(Benzyloxy)-4-bromo-1-nitrobenzene (CAS 849210-10-2)
- 2-((4-Methoxyphenyl)sulfonamido)thiazole-4-carboxylic acid (CAS 1105192-75-3)
- (S)-6-(Trifluoromethyl)chroman-4-amine hydrochloride (CAS 2088960-08-9)
- N-cyclohexyl-4-hydroxyisoxazolidine-2-carboxamide (CAS 344276-21-7)
- 2-(Piperidin-4-yloxy)benzoic acid hydrochloride (CAS 1332531-16-4)
- 2-Oxo-2-(10H-phenothiazin-10-yl)ethyl 2-(furan-2-carboxamido)benzoate (CAS 474386-43-1)
- Semaglutide Impurity 167 (CAS CATO-C4X-2226167)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com