5-Chloro-2-methyl-2,3-dihydrobenzofuran-7-carboxylic acid CAS 31457-04-2
| CAS No. | 31457-04-2 |
| Molecular Formula | C10H9ClO3 |
| Molecular Weight | 212.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Chloro-2-methyl-2,3-dihydrobenzofuran-7-carboxylic acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-Chloro-2-methyl-2,3-dihydrobenzofuran-7-carboxylic acid (CAS 31457-04-2) is a high-purity analytical reference standard with the molecular formula C10H9ClO3 and a molecular weight of 212.63 g/mol.
5-Chloro-2-methyl-2,3-dihydrobenzofuran-7-carboxylic acid (C10H9ClO3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Chloro-2-methyl-2,3-dihydrobenzofuran-7-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H9ClO3 |
| Molecular Weight | 212.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Halogen Content | Cl-containing |
Related Chloro Standards
- 4-Chloro-2-cyano-3-fluorophenylisothiocyanate (CAS 1000577-97-8)
- 2-(5-chloro-2,3-dihydro-1-benzofuran-2-yl)acetic acid (CAS 1018251-39-2)
- 2-Chloro-3-cyclopropoxybenzoic acid (CAS 1036204-45-1)
- Ethyl 2-chloro-6-formylbenzoate (CAS 1049677-64-6)
- 7-Chloro-3-ethyl-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one (CAS 105544-35-2)
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- Methyl 2-chloro-6-cyclopropylpyrimidine-4-carboxylate (CAS 1175925-40-2)
- 3-Chloro-2-cyclopropoxybenzoic acid (CAS 1243318-45-7)
Recommended Standards
- 5-Chloro-2-cyclopropoxybenzoic acid (CAS 959749-03-2)
- 5-Chloro-3-methyl-2,3-dihydrobenzofuran-2-carboxylic acid (CAS 230293-44-4)
- 4-Chloro-N-cyclopropyl-2-nitroaniline (CAS 304914-98-5)
- 6-Chlorochroman-2-carboxylic acid (CAS 40026-24-2)
- 2-(4-Cyclohexylphenyl)butanoic acid (CAS 41641-69-4)
- 1-(Azepan-2-ylmethyl)azepane (CAS 881040-52-4)
- 3-Fluoroimidazo[1,2-b]pyridazine-6-carboxylic acid (CAS 1315360-95-2)
- 3-[2-(Trifluoromethyl)-1,3-thiazol-4-yl]aniline (CAS 1401522-25-5)
- 2-(3,5-Dichlorophenoxy)ethanethioamide (CAS 119024-27-0)
- 5-Bromo-2-propoxybenzamide (CAS 882093-01-8)
- 2-(2,4-Difluorophenyl)cyclopropan-1-amine (CAS 1001318-18-8)
- Ethyl 7-chloro-6-formyl-2-propionamido-4,5-dihydrobenzo[b]thiophene-3-carboxylate (CAS 137987-67-8)
- 5-Fluoro-2-methylpyridine-3-sulfonyl chloride (CAS 2505373-53-3)
- Semaglutide impurity 211 (CAS CATO-C4X-2226211)
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