6-Phenylthieno[2,3-d]pyrimidine-4-thiol CAS 315685-01-9
| CAS No. | 315685-01-9 |
| Molecular Formula | C12H8N2S2 |
| Molecular Weight | 244.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-Phenylthieno[2,3-d]pyrimidine-4-thiol (CAS 315685-01-9) is a high-purity analytical reference standard with the molecular formula C12H8N2S2 and a molecular weight of 244.34 g/mol.
The molecular framework of 6-Phenylthieno[2,3-d]pyrimidine-4-thiol (C12H8N2S2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H8N2S2 |
| Molecular Weight | 244.34 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Phenylthieno Standards
- 5-Phenylthieno[2,3-d]pyrimidine-4-thiol (CAS 182198-89-6)
- 3-Phenylthieno[3,2-d]pyrimidine-2,4(1H,3H)-dione (CAS 16233-52-6)
- 6-Phenylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione (CAS 86126-60-5)
- 6-Phenylthieno[3,2-d]pyrimidine-2,4-diamine (CAS 109879-88-1)
- 2-Methyl-6-phenylthieno[3,2-d]pyrimidin-4-ol (CAS 156424-47-4)
- 2-Methyl-6-phenylthieno[2,3-d]pyrimidin-4(3H)-one (CAS 18593-59-4)
- 2-Methyl-5-phenylthieno[2,3-d]pyrimidin-4(3H)-one (CAS 18593-67-4)
- 6-Methyl-5-phenylthieno[2,3-d]pyrimidin-4(1H)-one (CAS 35978-38-2)
Recommended Standards
- 5,10-Bisdimethylamino-5H,10H-dipyrrolo[1,2-a:-1',2'-d]pyrazine, 97% (CAS 64435-30-9)
- CGP 52608 (CAS 87958-67-6)
- 5-(Naphthalen-2-ylsulfanyl)-1,2,3-thiadiazole (CAS 400083-63-8)
- N-((1H-benzo[d][1,2,3]triazol-1-yl)methyl)-N-methylcyclohexanamine (CAS 57684-31-8)
- (3S)-3-amino-5,5-dimethyloxolan-2-one (CAS 77443-32-4)
- 3-Chloro-2-fluoro-6-methylpyridine (CAS 1227574-35-7)
- 2-Methoxy-N-(2-(piperidin-1-yl)ethyl)acetamide (CAS 1252461-45-2)
- L-Ala-NCA (CAS 2224-52-4)
- 3-Fluoro-N-(3-fluorobenzyl)aniline (CAS 637744-58-2)
- 4-(Aminomethyl)-3-(tert-butoxy)phenol (CAS 1243414-77-8)
- 2-Chloro-2-pyrrolidinomethyl benzophenone (CAS 898774-75-9)
- 2-(3-(Tert-butyl)ureido)benzoic acid (CAS 13223-99-9)
- 4-Methyl-6-propoxypyridin-3-amine (CAS 1540599-32-3)
- Galanin Message Associated Peptide (1-41) amide trifluoroacetate salt (CAS 132699-74-2)
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