5-Fluorouridine CAS 316-46-1
| CAS No. | 316-46-1 |
| Molecular Formula | C9H11FN2O6 |
| Molecular Weight | 262.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
5-Fluorouridine (CAS 316-46-1), molecular formula C9H11FN2O6 and molecular weight 262.19 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C9H11FN2O6, 5-Fluorouridine contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 262.19 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 5-Fluorouridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H11FN2O6 |
| Molecular Weight | 262.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluorouridine Standards
Recommended Standards
- 5-Fluoro-3-(3-oxo-1,3-dihydroisobenzofuran-1-yl)pyrimidine-2,4(1H,3H)-dione (CAS 82023-29-8)
- Benzyl 2-(2,2,2-trifluoroacetyl)hydrazinecarboxylate (CAS 866478-74-2)
- 5-Fluoro-1-(3-oxo-1,3-dihydroisobenzofuran-1-yl)pyrimidine-2,4(1H,3H)-dione (CAS 81820-68-0)
- 1-(2,5-dimethylphenyl)-1-phenylpropan-1-ol 57988-58-6 KST-1B5838 (CAS 57988-58-6)
- N-[4-(tert-Butyl)benzyl]-3-(2-phenoxyethoxy)-aniline (CAS 1040686-14-3)
- (2,3-Dichloro-6-fluorophenyl)(methyl)sulfane (CAS 1803820-09-8)
- 1-(2-(Hydroxymethyl)phenyl)piperidin-4-ol hydrochloride (CAS 1189437-95-3)
- 2-Phenylpyrrolidine-2-carboxylic acid hydrochloride (CAS 308841-68-1)
- N-(morpholin-2-ylmethyl)methanesulfonamide hydrochloride (CAS 1219832-49-1)
- cis-Dichlorbis(2,2'-bipyrazine)dichlororuthenium (CAS 80907-59-1)
- 2-Bromo-5-(2-fluoroethoxy)-4-methylpyridine (CAS 1841080-24-7)
- 1,1,2,3-Tetramethyl-1H-benzo[e]indol-3-ium iodide (CAS 58464-25-8)
- (1-(3-Fluorophenyl)-1h-tetrazol-5-yl)methanamine hydrochloride (CAS 1426291-28-2)
- Semaglutide Impurity 128 (CAS 2490269-78-6)
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