N-(4-Chloro-3-(trifluoromethyl)phenyl)-2-methoxybenzamide CAS 316128-15-1
| CAS No. | 316128-15-1 |
| Molecular Formula | C15H11ClF3NO2 |
| Molecular Weight | 329.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of N-(4-Chloro-3-(trifluoromethyl)phenyl)-2-methoxybenzamide (C15H11ClF3NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies N-(4-Chloro-3-(trifluoromethyl)phenyl)-2-methoxybenzamide (CAS 316128-15-1), a certified reference material (molecular formula C15H11ClF3NO2, MW 329.70 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(4-Chloro-3-(trifluoromethyl)phenyl)-2-methoxybenzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H11ClF3NO2 |
| Molecular Weight | 329.70 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related N Standards
- 2-[2-Chloro-5-(trifluoromethyl)pyridin-4-ylamino]-N-methylbenzamide (CAS 1061358-71-1)
- Ethyl 2-chloro-6-(4-trifluorophenyl)nicotinate (CAS 1261802-95-2)
- 4-(6-Chloro-4-trifluoromethyl-pyridin-2-yl)-benzoic acid ethyl ester (CAS 1311278-42-8)
- N'-(6-chloro-4-(trifluoromethyl)pyridin-2-yl)-N'-methylbenzohydrazide (CAS 1431555-17-7)
- N-[6-Chloro-4-(trifluoromethyl)pyridin-2-yl]-2-methylbenzohydrazide (CAS 1795304-95-8)
- 2-(4-Chloro-2-methylphenoxy)-2,2-difluoro-N-(4-fluorophenyl)acetamide (CAS 339011-04-0)
- 2-[3-Chloro-5-(trifluoromethyl)-2-pyridyl]-3-phenylpropanoic acid (CAS 1987008-07-0)
- 2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-[(pyridin-2-yl)methyl]acetamide (CAS 691873-26-4)
Recommended Standards
- 5-Chloro-4-(cyclopropylamino)-2-(3-(trifluoromethyl)phenyl)pyridazin-3(2H)-one (CAS 65269-77-4)
- N-[6-Chloro-4-(trifluoromethyl)-2-pyridyl]-N'-(2-methylphenyl)urea (CAS 256471-17-7)
- 4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}phenyl acetate (CAS 338410-48-3)
- N-[6-Chloro-4-(trifluoromethyl)-2-pyridyl]-N'-(3-methylphenyl)urea (CAS 256471-18-8)
- 5-(4-Aminobenzyl)thiazolidine-2,4-dione (CAS 85002-36-4)
- 2-(3-Amino-1h-pyrazol-1-yl)-N-ethyl-N-methylacetamide (CAS 1183698-45-4)
- (3-(3-Ethoxypropoxy)-4-methylphenyl)boronic acid (CAS 1704067-37-7)
- (1-(But-2-yn-1-yl)-1H-pyrazol-4-yl)methanamine (CAS 1342214-82-7)
- 1-(2-Amino-[1,1'-biphenyl]-4-yl)ethanone (CAS 42771-78-8)
- (S)-Methyl 1-((methoxycarbonyl)amino)pyrrolidine-2-carboxylate (CAS 134920-22-2)
- 3-Bromopropane-1-sulfonamide (CAS 88496-95-1)
- 3-Amino-3-methylpentan-1-ol (CAS 51973-07-0)
- 1-[(R)-phenyl(4-phenylphenyl)methyl]-1H-imidazole (CAS 91487-85-3)
- Semaglutide Impurity 188 (CAS CATO-C4X-2226188)
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