(2Z)-3-(4-Chlorophenyl)-2-(4-iodophenyl)-acrylic acid CAS 3163-82-4
| CAS No. | 3163-82-4 |
| Molecular Formula | C15H10ClIO2 |
| Molecular Weight | 384.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (2Z)-3-(4-Chlorophenyl)-2-(4-iodophenyl)-acrylic acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/iodine substitution, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(2Z)-3-(4-Chlorophenyl)-2-(4-iodophenyl)-acrylic acid (CAS 3163-82-4) is a high-purity analytical reference standard with the molecular formula C15H10ClIO2 and a molecular weight of 384.60 g/mol.
The molecular framework of (2Z)-3-(4-Chlorophenyl)-2-(4-iodophenyl)-acrylic acid (C15H10ClIO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/iodine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H10ClIO2 |
| Molecular Weight | 384.60 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl/I-containing |
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Recommended Standards
- N1-((8R,9S,13S,14S,17S)-3-methoxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-17-yl)hexane-1,6-diamine (CAS 112646-70-5)
- (S)-6-Amino-2-palmitamidohexanoic acid (CAS 59866-71-6)
- Selumetinib Impurity 8 (CAS CATO-C4X-30538)
- [2,2'-Bi[1,3]dithiolo[4,5-d][1,3]dithiolylidene]-5,5'-dione (CAS 64394-47-4)
- Vonoprazan (CAS 881681-00-1)
- (R)-Ethyl 3-oxocyclohexanecarboxylate (CAS 2043662-34-4)
- methyl 5-fluoro-[1,3]thiazolo[5,4-b]pyridine-2-carboxylate (CAS 1440427-98-4)
- Finerenone Impurity 205 (CAS 890705-78-9)
- 15871-63-3 ETHANONE,1-[4-(2-HYDROXYETHYL)-1-PIPERIDINYL]- SC-61098 (CAS 15871-63-3)
- 1713160-83-8 4-(3,3-Difluoropyrrolidin-1-yl)-3-nitrobenzaldehyde (CAS 1713160-83-8)
- Lacosamide Impurity 58 (CAS CATO-C4X-183058)
- 4-(2-Aminopropyl)-1H-imidazole-2(3H)-thione (CAS 806625-87-6)
- Azetidin-3-yl 2,2,2-trichloroacetate (CAS 1219956-76-9)
- Insulin Degludec Impurity 28 (CAS CATO-C4X-215728)
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