4-(Benzo[d]oxazol-2-yl)-2-methoxyphenol CAS 3164-07-6
| CAS No. | 3164-07-6 |
| Molecular Formula | C14H11NO3 |
| Molecular Weight | 241.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-(Benzo[d]oxazol-2-yl)-2-methoxyphenol (C14H11NO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
4-(Benzo[d]oxazol-2-yl)-2-methoxyphenol (CAS 3164-07-6) is a high-purity analytical reference standard with the molecular formula C14H11NO3 and a molecular weight of 241.24 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(Benzo[d]oxazol-2-yl)-2-methoxyphenol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H11NO3 |
| Molecular Weight | 241.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- 4-((2-Hydroxybenzylidene)amino)benzoic acid (CAS 788-24-9)
- Tert-butyl (3-oxo-4-(pyridin-2-yl)butan-2-yl)carbamate (CAS 1259520-73-4)
- 2-(1-Phenethylpiperidin-4-yl)ethan-1-amine (CAS 132740-58-0)
- 2,4-Dimethyl-5-oxazolecarboxylic Acid (CAS 2510-37-4)
- 4-(((1R,4r)-4-aminocyclohexyl)oxy)benzonitrile hydrochloride (CAS 1335048-90-2)
- 1-(2,4-Dichlorobenzyl)-3-phenyl-1H-pyrazole-4-carbaldehyde (CAS 312275-55-1)
- Milnacipran Impurity 23 (CAS CATO-C4X-103323)
- N-(4-((3-(Thiophene-2-sulfonamido)quinoxalin-2-yl)amino)phenyl)acetamide (CAS 714920-64-6)
- N-((1H-imidazol-5-yl)methyl)-1-(4-methoxyphenyl)methanamine (CAS 1341516-49-1)
- 2-Bromo-3-bromomethyl-4-(trifluoromethyl)pyridine (CAS 1227516-34-8)
- Semaglutide Impurity 137 (x TFA Salt) (CAS CATO-C4X-2226137)
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