N,N′-Bis(2-chloroethyl)phosphorodiamidic acid CAS 31645-39-3

Purity 97%+In StockPharmaceutical Standards
CAS No.31645-39-3
Molecular FormulaC4H11Cl2N2O2P
Molecular Weight221.02 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N,N′-Bis(2-chloroethyl)phosphorodiamidic acid CAS 31645-39-3 chemical structure

Description

The occurrence of N,N′-Bis(2-chloroethyl)phosphorodiamidic acid is closely related to an amide group, organophosphorus functionality, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies N,N′-Bis(2-chloroethyl)phosphorodiamidic acid (CAS 31645-39-3), a certified reference material (molecular formula C4H11Cl2N2O2P, MW 221.02 g/mol) for analytical method development and quality control.

The molecular framework of N,N′-Bis(2-chloroethyl)phosphorodiamidic acid (C4H11Cl2N2O2P) is characterized by an amide group, organophosphorus functionality, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures N,N′-Bis(2-chloroethyl)phosphorodiamidic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC4H11Cl2N2O2P
Molecular Weight221.02 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)-0.5
CAS Registry Year (est.)1966
Halogen ContentCl-containing
Nitrogen Atoms2

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