3-Ethyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole-6-thiol CAS 3173-12-4

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

3-Ethyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole-6-thiol (CAS 3173-12-4), molecular formula C5H6N4S2 and molecular weight 186.26 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 3-Ethyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole-6-thiol (C5H6N4S2) is characterized by a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

As a certified reference material (CRM), 3-Ethyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole-6-thiol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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