tert-Butyl 4,4-difluoro-2-formylpyrrolidine-1-carboxylate CAS 317357-15-6
| CAS No. | 317357-15-6 |
| Molecular Formula | C10H15F2NO3 |
| Molecular Weight | 235.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of tert-Butyl 4,4-difluoro-2-formylpyrrolidine-1-carboxylate (C10H15F2NO3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies tert-Butyl 4,4-difluoro-2-formylpyrrolidine-1-carboxylate (CAS 317357-15-6), a certified reference material (molecular formula C10H15F2NO3, MW 235.23 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures tert-Butyl 4,4-difluoro-2-formylpyrrolidine-1-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H15F2NO3 |
| Molecular Weight | 235.23 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- Tert-butyl 3,3-difluoro-4-formylpyrrolidine-1-carboxylate (CAS 2287955-97-7)
- tert-Butyl 5,5-difluoro-2-oxopiperidine-1-carboxylate (CAS 911634-76-9)
- O-Methyl 3-(trifluoromethyl)phenylcarbamothioate (CAS 658039-45-3)
- Methyl 5-(1-ethyl-5-methyl-1h-pyrazol-4-yl)isoxazole-3-carboxylate (CAS 1001519-01-2)
- 1-(3-Chlorophenyl)-4-hydroxy-6-oxo-1,6-dihydropyridazine-3-carboxamide (CAS 303150-43-8)
- 2-(1H-Pyrrol-1-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1309981-28-9)
- 3-Methyl-1H-pyrrole-2-carbonitrile (CAS 24014-22-0)
- 2-(6-Bromo-4-(difluoromethyl)-5-iodopyridin-3-yl)acetonitrile (CAS 1807010-71-4)
- Zinc dihydrogen phosphate (CAS 13598-37-3)
- 4-Chloro-2-(chloromethyl)-3-(trifluoromethyl)pyridine (CAS 1393584-17-2)
- Cyclohexyl methyl ketone (CAS 823-76-7)
- (S)-tert-Butyl (2-(hydroxymethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-6-yl)carbamate (CAS 2648219-62-7)
- 4-(1,3,4-Oxadiazol-2-yl)aniline (CAS 35219-13-7)
- Semaglutide impurity 23 (CAS CATO-C4X-222623)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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