4-(2,4-Difluorobenzoyl)-3-methyl-3,4-dihydroquinoxalin-2(1H)-one CAS 317822-35-8

Purity 97%+In StockPharmaceutical Standards
CAS No.317822-35-8
Molecular FormulaC16H12F2N2O2
Molecular Weight302.28 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-(2,4-Difluorobenzoyl)-3-methyl-3,4-dihydroquinoxalin-2(1H)-one CAS 317822-35-8 chemical structure

Description

4-(2,4-Difluorobenzoyl)-3-methyl-3,4-dihydroquinoxalin-2(1H)-one (CAS 317822-35-8), molecular formula C16H12F2N2O2 and molecular weight 302.28 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 4-(2,4-Difluorobenzoyl)-3-methyl-3,4-dihydroquinoxalin-2(1H)-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 302.28 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 4-(2,4-Difluorobenzoyl)-3-methyl-3,4-dihydroquinoxalin-2(1H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC16H12F2N2O2
Molecular Weight302.28 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing
Nitrogen Atoms2

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