1-[(4-Chlorophenyl)methyl]-3-methyl-4-(4-methylbenzoyl)-1,2,3,4-tetrahydroquinoxalin-2-one CAS 317822-41-6
| CAS No. | 317822-41-6 |
| Molecular Formula | C24H21ClN2O2 |
| Molecular Weight | 404.89 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-[(4-Chlorophenyl)methyl]-3-methyl-4-(4-methylbenzoyl)-1,2,3,4-tetrahydroquinoxalin-2-one.
1-[(4-Chlorophenyl)methyl]-3-methyl-4-(4-methylbenzoyl)-1,2,3,4-tetrahydroquinoxalin-2-one (CAS 317822-41-6), molecular formula C24H21ClN2O2 and molecular weight 404.89 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 1-[(4-Chlorophenyl)methyl]-3-methyl-4-(4-methylbenzoyl)-1,2,3,4-tetrahydroquinoxalin-2-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 404.89 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H21ClN2O2 |
| Molecular Weight | 404.89 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorophenyl Standards
- 1-(2-Chlorophenyl)-N-(3-phenylpropyl)-5-(1H-pyrrol-1-yl)-1H-pyrazole-4-carboxamide (CAS 1206997-67-2)
- 2-((3-(4-Chlorophenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)-5,5-dimethylcyclohexane-1,3-dione (CAS 313273-04-0)
- 2-(4-Chlorophenyl)-N-(3-(5,7-dimethylbenzo[d]oxazol-2-yl)-2-methylphenyl)acetamide (CAS 590395-88-3)
- 3-(4-((2-Chlorophenyl)sulfonyl)piperazin-1-yl)-6-(furan-2-yl)pyridazine (CAS 1021099-83-1)
- 2-[2-(2-Chlorophenyl)-4-phenyl-1,3-thiazol-5-yl]-N-phenylacetamide (CAS 338957-25-8)
- 2-[2-(4-chlorophenyl)-4-phenyl-1,3-thiazol-5-yl]-N-phenylacetamide (CAS 338957-14-5)
- 3-((2-(4-Chlorophenyl)-2-oxoethyl)thio)-1-phenyl-6,7-dihydro-5H-cyclopenta[c]pyridine-4-carbonitrile (CAS 439108-56-2)
- 3-((4-Chlorophenyl)thio)-N-methyl-2-phenylquinoline-4-carboxamide (CAS 400078-38-8)
Recommended Standards
- Tert-butyl (1-(6-chloro-2-phenoxypyrimidin-4-yl)piperidin-3-yl)carbamate (CAS 1334149-00-6)
- Dapagliflozin impurity 16 (CAS CATO-C4X-1138216)
- 2-Chloro-N-(3-(5,7-dimethylbenzo[d]oxazol-2-yl)-2-methylphenyl)-4-methylbenzamide (CAS 590395-96-3)
- 3,4,6-Tribromodibenzo[b,d]furan (CAS 617707-56-9)
- tert-Butyl 4-(4-chloro-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate (CAS 791852-35-2)
- 6-(4-Methylphenoxy)pyridin-3-amine (CAS 752969-65-6)
- N-Butyl 2-bromo-5-fluorobenzamide (CAS 951884-19-8)
- methyl 2-{4-chloropyrrolo[2,1-f][1,2,4]triazin-7-yl}acetate (CAS 2090909-29-6)
- (R)-9-(2,3-Dihydroxy-3-methylbutoxy)-7H-furo[3,2-g]chromen-7-one (CAS 31575-93-6)
- (R)-2-(4-Fluorophenyl)-2-hydroxyacetonitrile (CAS 149952-37-4)
- 2-(6-(2-Aminoethyl)pyridin-2-yl)propan-2-ol (CAS 2798825-95-1)
- Bempedoic Acid Impurity 2 (CAS 738606-64-9)
- (2R,3R,4S)-3-amino-2,4,5-trihydroxypentanal hydrochloride (CAS 20590-58-3)
- Semaglutide impurity 24 (CAS CATO-C4X-222624)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com