1-[(2,4-Dichlorophenyl)methyl]-4-(4-fluorobenzoyl)-3-methyl-1,2,3,4-tetrahydroquinoxalin-2-one CAS 317833-35-5
| CAS No. | 317833-35-5 |
| Molecular Formula | C23H17Cl2FN2O2 |
| Molecular Weight | 443.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 443.30 g/mol gives 1-[(2,4-Dichlorophenyl)methyl]-4-(4-fluorobenzoyl)-3-methyl-1,2,3,4-tetrahydroquinoxalin-2-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-[(2,4-Dichlorophenyl)methyl]-4-(4-fluorobenzoyl)-3-methyl-1,2,3,4-tetrahydroquinoxalin-2-one (CAS 317833-35-5) is a high-purity analytical reference standard with the molecular formula C23H17Cl2FN2O2 and a molecular weight of 443.30 g/mol.
The molecular framework of 1-[(2,4-Dichlorophenyl)methyl]-4-(4-fluorobenzoyl)-3-methyl-1,2,3,4-tetrahydroquinoxalin-2-one (C23H17Cl2FN2O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-[(2,4-Dichlorophenyl)methyl]-4-(4-fluorobenzoyl)-3-methyl-1,2,3,4-tetrahydroquinoxalin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H17Cl2FN2O2 |
| Molecular Weight | 443.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichlorophenyl Standards
- 1-[(2,6-Dichlorophenyl)methyl]-4-(4-fluorobenzoyl)-3-methyl-1,2,3,4-tetrahydroquinoxalin-2-one (CAS 317833-38-8)
- 4-(4-(2,4-Dichlorophenyl)thiazol-2-yl)-N-(4-fluorophenyl)benzamide (CAS 321430-04-0)
- (2E)-1-{3-[(2,4-dichlorophenyl)methoxy]phenyl}-3-[(3-nitrophenyl)amino]prop-2-en-1-one (CAS 478040-35-6)
- N-(2,5-Dichlorophenyl)-4-((2,6-dimethylmorpholino)sulfonyl)benzamide (CAS 325746-12-1)
- 6-(2,6-Dichlorophenyl)-8-methyl-2-((3-(methylthio)phenyl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one (CAS 260415-63-2)
- 3-({[(2,6-dichlorophenyl)methyl]sulfanyl}methyl)-4-ethyl-5-{[(4-fluorophenyl)methyl]sulfanyl}-4H-1,2,4-triazole (CAS 344273-75-2)
- N-(2,5-Dichlorophenyl)-2-((3-ethyl-5,6-dimethyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio)acetamide (CAS 335399-74-1)
- N-(3,4-Dichlorophenyl)-2-((3-ethyl-5,6-dimethyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio)acetamide (CAS 618427-83-1)
Recommended Standards
- 1-(4-((2-(4-Iodophenoxy)thiazol-5-yl)methyl)piperazin-1-yl)ethan-1-one (CAS 866020-50-0)
- 1-(3,4-Dichlorobenzyl)-4-(4-fluorobenzoyl)-3-methyl-3,4-dihydroquinoxalin-2(1H)-one (CAS 317833-40-2)
- 1-[(2-Chloro-6-fluorophenyl)methyl]-4-(4-chlorobenzoyl)-3-methyl-1,2,3,4-tetrahydroquinoxalin-2-one (CAS 317822-31-4)
- (Z)-(1-{3-[(4-chlorobenzenesulfonyl)methyl]-4-nitrophenyl}ethylidene)({[(2E)-3-chloroprop-2-en-1-yl]oxy})amine (CAS 339016-34-1)
- (-)-2-Azabicyclo[2.2.1]hept-5-en-3-one (-)-Vince Lactam (1R)-(-)-2-Azabicyclo[2.2.1]hept-5-en-3-one (1R,4S)-2-Azabicyclo[2.2.1]hept-5-en-3-one 79200-56-9 (CAS 79200-56-9)
- 2-[4-(5-Methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H-pyrido[1,2-c]pyrimidin-2-yl]-N-(2,4,6-trimethylphenyl)acetamide (CAS 1775337-05-7)
- 6-(Benzyloxy)-3-bromo-2-methylpyridine (CAS 126717-60-0)
- 3-Mercapto-2-naphthoic acid (CAS 24156-00-1)
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- 5-Isobutyramido-1-methyl-1H-pyrazole-3-carboxylic acid (CAS 1239753-88-8)
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