6-Methyl-2-((2-(piperidin-1-yl)ethyl)thio)-4-(trifluoromethyl)nicotinonitrile CAS 317844-64-7
| CAS No. | 317844-64-7 |
| Molecular Formula | C15H18F3N3S |
| Molecular Weight | 329.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
6-Methyl-2-((2-(piperidin-1-yl)ethyl)thio)-4-(trifluoromethyl)nicotinonitrile (CAS 317844-64-7), molecular formula C15H18F3N3S and molecular weight 329.38 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 6-Methyl-2-((2-(piperidin-1-yl)ethyl)thio)-4-(trifluoromethyl)nicotinonitrile (C15H18F3N3S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 329.38 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H18F3N3S |
| Molecular Weight | 329.38 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Methyl Standards
- 5-(Piperidin-1-ylsulfonyl)thiophene-2-sulfonyl chloride (CAS 1306607-14-6)
- 5-(Piperidin-1-yl(p-tolyl)methyl)thiazolo[3,2-b][1,2,4]triazol-6-ol (CAS 868219-39-0)
- Piperidin-1-yl(2-((3,4,4-trifluorobut-3-en-1-yl)thio)pyridin-3-yl)methanone (CAS 339106-90-0)
- 7-(Piperidin-1-ylmethyl)quinolin-8-ol (CAS 6632-09-3)
- 2-{[2-(piperidin-1-yl)-1,3-thiazol-5-yl]methyl}-2,3-dihydro-1H-isoindole-1,3-dione (CAS 866136-90-5)
- 2-(3-(Piperidin-1-yl)pyrrolidin-1-yl)benzo[d]thiazole-6-carboxylic acid (CAS 1161731-03-8)
- 1-{4-[3-(piperidin-1-yl)propoxy]benzoyl}piperazine dihydrochloride (CAS 685871-07-2)
- 2-(piperidin-1-ylmethyl)-5-(thiophen-2-yl)-3H,4H-thieno[2,3-d]pyrimidin-4-one (CAS 255378-91-7)
Recommended Standards
- 6-[(4-Ethyl-5-sulfanyl-4H-1,2,4-triazol-3-yl)methoxy]-2-phenyl-2,3-dihydropyridazin-3-one (CAS 866136-77-8)
- 7-Bromo-2,4,6-trichloro-8-fluoroquinoline (CAS 2728716-41-2)
- 5-Nitro-6-(4-phenylpiperazin-1-yl)imidazo[2,1-b]thiazole (CAS 339021-38-4)
- Ethyl 2-((3-(pyridin-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)thio)propanoate (CAS 868968-20-1)
- 1-(4-Methoxyphenyl)-2-thiocyanatoethanone (CAS 6097-26-3)
- 4-Hydroxy-3-nitro-2-(trifluoromethoxy)pyridine-6-sulfonyl chloride (CAS 1806736-85-5)
- Ethyl 5-(bromomethyl)furan-2-carboxylate (CAS 74675-71-1)
- 5-(Chloromethyl)-1-ethyl-1H-1,2,4-triazole (CAS 252750-52-0)
- 2-Nitro-5-(propylthio)aniline (CAS 57780-75-3)
- 3-chloroimidazo[1,5-a]pyridine-1-carbaldehyde (CAS 1936356-88-5)
- tert-Butyl 14-(N-Boc-amino)-1-[3-(methoxycarbonyl)phenoxy]-13,15-dioxo-3,6,9-trioxa- 12,16-diazanonadecan-19-oate (CAS 1076199-61-5)
- 5-Bromo-2-methylsulfanylmethyl-pyridine (CAS 1566292-79-2)
- Bcx 1470 (CAS 217099-43-9)
- Tau Peptide (512-525) amide trifluoroacetate salt (CAS 2022956-61-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com