Ethyl 6-Fluoro-4-hydroxyquinoline-3-carboxylate CAS 318-35-4
| CAS No. | 318-35-4 |
| Molecular Formula | C12H10FNO3 |
| Molecular Weight | 235.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 6-Fluoro-4-hydroxyquinoline-3-carboxylate.
Ethyl 6-Fluoro-4-hydroxyquinoline-3-carboxylate (CAS 318-35-4), molecular formula C12H10FNO3 and molecular weight 235.21 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Ethyl 6-Fluoro-4-hydroxyquinoline-3-carboxylate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 235.21 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Ethyl 6-Fluoro-4-hydroxyquinoline-3-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H10FNO3 |
| Molecular Weight | 235.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- 3-(6-Fluoro-2-oxo-1,2-dihydroquinolin-3-yl)propanoic acid (CAS 1017249-93-2)
- 1-Ethyl-8-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 1018135-10-8)
- 1-(3-Fluoro-4-methylphenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acid (CAS 1031578-62-7)
- 2-(8-Fluoro-2-methyl-4-oxoquinolin-1(4H)-yl)acetic acid (CAS 1083197-24-3)
- 1-(2-Fluoro-4-methylphenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acid (CAS 1094373-32-6)
- Methyl 2-(6-fluoro-4-oxoquinolin-1(4H)-yl)acetate (CAS 1171941-16-4)
- 1-(4-Fluoro-3-methylphenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acid (CAS 1239728-42-7)
- Methyl 6-fluoro-4-methoxyquinoline-2-carboxylate (CAS 1260877-10-8)
Recommended Standards
- Ethyl 6-fluoro-3-formyl-1H-indole-2-carboxylate (CAS 586336-90-5)
- Ethyl 6-fluoro-4-oxo-1H-quinoline-3-carboxylate (CAS 71083-00-6)
- Ethyl 5-fluoro-4-hydroxyquinoline-3-carboxylate (CAS 655236-29-6)
- Ethyl 7-fluoro-4-hydroxyquinoline-3-carboxylate (CAS 26892-97-7)
- 2-(Benzylthio)-4,6-dichloro-1,3,5-triazine (CAS 25713-57-9)
- 2-(Difluoromethyl)-4-Methyl-1,3-Oxazol-5(2H)-One (CAS 154140-57-5)
- 1-Iodo-4-(2,2,2-trifluoroethyl)benzene (CAS 1393544-55-2)
- Ethyl 2-ethylcyclopropanecarboxylate (CAS 115188-22-2)
- N-(Pyrrolidin-2-ylmethyl)naphthalen-1-amine dioxalate (CAS 1177290-60-6)
- Pyrene-1,6-dicarbaldehyde (CAS 252338-01-5)
- Ethyl 3-amino-2-hydroxybenzoate (CAS 172092-29-4)
- 4-((2,2,2-Trifluoroethyl)amino)benzoic acid (CAS 892878-66-9)
- 7-Boc-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine (CAS 374795-76-3)
- (Glu1)-Fibrinopeptide B (human) (CAS 103213-49-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com